MT-CYB | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
B cell	49 studies	90% ± 17%	Explore
macrophage	45 studies	81% ± 24%	Explore
natural killer cell	44 studies	90% ± 15%	Explore
endothelial cell	43 studies	81% ± 22%	Explore
fibroblast	41 studies	82% ± 27%	Explore
T cell	39 studies	90% ± 15%	Explore
CD8-positive, alpha-beta T cell	37 studies	89% ± 17%	Explore
pericyte	36 studies	83% ± 26%	Explore
CD4-positive, alpha-beta T cell	35 studies	86% ± 22%	Explore
conventional dendritic cell	31 studies	93% ± 14%	Explore
smooth muscle cell	30 studies	85% ± 22%	Explore
dendritic cell	28 studies	85% ± 21%	Explore
mast cell	28 studies	79% ± 26%	Explore
plasmacytoid dendritic cell	27 studies	91% ± 10%	Explore
monocyte	26 studies	83% ± 21%	Explore
plasma cell	25 studies	87% ± 19%	Explore
endothelial cell of lymphatic vessel	25 studies	89% ± 14%	Explore
classical monocyte	25 studies	90% ± 16%	Explore
regulatory T cell	25 studies	95% ± 9%	Explore
non-classical monocyte	24 studies	88% ± 21%	Explore
epithelial cell	23 studies	85% ± 23%	Explore
mature NK T cell	22 studies	90% ± 13%	Explore
gamma-delta T cell	21 studies	95% ± 8%	Explore
basal cell	21 studies	86% ± 19%	Explore
memory B cell	20 studies	97% ± 6%	Explore
mucosal invariant T cell	18 studies	90% ± 20%	Explore
naive B cell	18 studies	92% ± 18%	Explore
connective tissue cell	18 studies	88% ± 16%	Explore
ciliated cell	17 studies	88% ± 14%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	17 studies	90% ± 19%	Explore
CD16-negative, CD56-bright natural killer cell, human	15 studies	84% ± 25%	Explore
capillary endothelial cell	15 studies	82% ± 18%	Explore
innate lymphoid cell	14 studies	91% ± 10%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	14 studies	95% ± 8%	Explore
CD16-positive, CD56-dim natural killer cell, human	14 studies	88% ± 21%	Explore
endothelial cell of artery	14 studies	87% ± 13%	Explore
erythrocyte	14 studies	69% ± 24%	Explore
microglial cell	14 studies	60% ± 28%	Explore
effector memory CD8-positive, alpha-beta T cell	13 studies	86% ± 22%	Explore
CD8-positive, alpha-beta memory T cell	13 studies	93% ± 12%	Explore
neutrophil	13 studies	73% ± 22%	Explore
astrocyte	13 studies	54% ± 26%	Explore
vein endothelial cell	13 studies	84% ± 13%	Explore
myeloid cell	13 studies	77% ± 29%	Explore
CD4-positive, alpha-beta memory T cell	12 studies	93% ± 11%	Explore
myofibroblast cell	12 studies	94% ± 10%	Explore
endothelial cell of vascular tree	12 studies	91% ± 15%	Explore
plasmablast	11 studies	97% ± 3%	Explore
secretory cell	11 studies	94% ± 10%	Explore
mesothelial cell	11 studies	86% ± 16%	Explore
type I pneumocyte	10 studies	74% ± 27%	Explore
platelet	10 studies	70% ± 26%	Explore
goblet cell	10 studies	98% ± 2%	Explore
IgG plasma cell	10 studies	83% ± 15%	Explore
type II pneumocyte	9 studies	79% ± 24%	Explore
T follicular helper cell	9 studies	95% ± 5%	Explore
club cell	9 studies	73% ± 25%	Explore
respiratory goblet cell	9 studies	81% ± 23%	Explore
oligodendrocyte	9 studies	49% ± 18%	Explore
leukocyte	9 studies	88% ± 20%	Explore
IgA plasma cell	9 studies	81% ± 20%	Explore
hematopoietic stem cell	9 studies	95% ± 8%	Explore
glutamatergic neuron	8 studies	67% ± 17%	Explore
oligodendrocyte precursor cell	8 studies	47% ± 26%	Explore
progenitor cell	8 studies	96% ± 3%	Explore
alveolar macrophage	7 studies	90% ± 13%	Explore
mononuclear phagocyte	7 studies	87% ± 9%	Explore
abnormal cell	7 studies	78% ± 27%	Explore
enterocyte	7 studies	97% ± 2%	Explore
enteroendocrine cell	7 studies	93% ± 8%	Explore
brush cell	7 studies	80% ± 28%	Explore
glial cell	7 studies	80% ± 21%	Explore
adipocyte	7 studies	51% ± 22%	Explore
CD4-positive helper T cell	6 studies	91% ± 9%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	6 studies	78% ± 28%	Explore
hematopoietic precursor cell	6 studies	84% ± 30%	Explore
ionocyte	6 studies	95% ± 5%	Explore
GABAergic neuron	6 studies	52% ± 25%	Explore
epithelial cell of proximal tubule	6 studies	85% ± 18%	Explore
renal alpha-intercalated cell	6 studies	97% ± 4%	Explore
erythroblast	6 studies	67% ± 30%	Explore
transit amplifying cell	6 studies	79% ± 29%	Explore
lymphocyte	6 studies	71% ± 37%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	98% ± 2%	Explore
neuron	6 studies	79% ± 11%	Explore
effector CD8-positive, alpha-beta T cell	6 studies	95% ± 7%	Explore
central memory CD8-positive, alpha-beta T cell	5 studies	95% ± 9%	Explore
hepatocyte	5 studies	78% ± 17%	Explore
interneuron	5 studies	70% ± 27%	Explore
kidney loop of Henle epithelial cell	5 studies	74% ± 32%	Explore
kidney distal convoluted tubule epithelial cell	5 studies	97% ± 2%	Explore
megakaryocyte	5 studies	90% ± 7%	Explore
intestinal crypt stem cell	5 studies	83% ± 31%	Explore
retinal cone cell	5 studies	71% ± 29%	Explore
retinal rod cell	5 studies	65% ± 28%	Explore
inflammatory macrophage	5 studies	88% ± 8%	Explore
effector CD4-positive, alpha-beta T cell	5 studies	92% ± 14%	Explore
melanocyte	5 studies	98% ± 1%	Explore
immature B cell	5 studies	99% ± 1%	Explore
CD4-positive, alpha-beta cytotoxic T cell	4 studies	81% ± 18%	Explore
deuterosomal cell	4 studies	90% ± 4%	Explore
duct epithelial cell	4 studies	92% ± 4%	Explore
exhausted T cell	4 studies	93% ± 7%	Explore
cholangiocyte	4 studies	69% ± 27%	Explore
endothelial cell of sinusoid	4 studies	74% ± 23%	Explore
podocyte	4 studies	92% ± 10%	Explore
paneth cell	4 studies	96% ± 3%	Explore
OFF-bipolar cell	4 studies	88% ± 17%	Explore
ON-bipolar cell	4 studies	95% ± 7%	Explore
retinal ganglion cell	4 studies	85% ± 22%	Explore
precursor B cell	4 studies	97% ± 2%	Explore
adventitial cell	4 studies	90% ± 14%	Explore
mucus secreting cell	4 studies	40% ± 19%	Explore
Mueller cell	4 studies	68% ± 26%	Explore
amacrine cell	4 studies	84% ± 19%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	97% ± 3%	Explore
IgM plasma cell	4 studies	84% ± 13%	Explore
intermediate monocyte	4 studies	91% ± 9%	Explore
keratinocyte	4 studies	94% ± 6%	Explore
T-helper 17 cell	4 studies	98% ± 1%	Explore
T-helper 1 cell	4 studies	97% ± 2%	Explore
double negative thymocyte	4 studies	98% ± 1%	Explore
Langerhans cell	3 studies	90% ± 13%	Explore
precursor cell	3 studies	81% ± 20%	Explore
squamous epithelial cell	3 studies	74% ± 26%	Explore
hepatic stellate cell	3 studies	74% ± 3%	Explore
glomerular endothelial cell	3 studies	98% ± 1%	Explore
kidney connecting tubule epithelial cell	3 studies	100% ± 0%	Explore
neural crest cell	3 studies	98% ± 1%	Explore
GABAergic amacrine cell	3 studies	75% ± 18%	Explore
glycinergic amacrine cell	3 studies	79% ± 14%	Explore
renal principal cell	3 studies	100% ± 1%	Explore
thymocyte	3 studies	98% ± 3%	Explore
pro-B cell	3 studies	98% ± 2%	Explore
neuroendocrine cell	3 studies	98% ± 1%	Explore
serous secreting cell	3 studies	56% ± 10%	Explore
cardiac muscle cell	3 studies	31% ± 16%	Explore
follicular B cell	3 studies	96% ± 3%	Explore
intraepithelial lymphocyte	3 studies	98% ± 0%	Explore
myoepithelial cell	3 studies	99% ± 1%	Explore
granulocyte	3 studies	87% ± 9%	Explore
luminal cell of prostate epithelium	3 studies	100% ± 0%	Explore
retina horizontal cell	3 studies	84% ± 13%	Explore
muscle cell	3 studies	61% ± 23%	Explore
ependymal cell	3 studies	52% ± 25%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	95% ± 7%	Explore
germinal center B cell	3 studies	79% ± 9%	Explore
group 3 innate lymphoid cell	3 studies	99% ± 1%	Explore
Schwann cell	3 studies	72% ± 36%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	97% ± 2%	Explore
double-positive, alpha-beta thymocyte	3 studies	98% ± 3%	Explore
progenitor cell of mammary luminal epithelium	3 studies	94% ± 2%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	18 studies	80% ± 20%	Explore
peripheral blood	17 studies	92% ± 10%	Explore
intestine	12 studies	94% ± 7%	Explore
brain	12 studies	59% ± 24%	Explore
kidney	7 studies	81% ± 22%	Explore
eye	7 studies	70% ± 28%	Explore
liver	6 studies	81% ± 11%	Explore
bone marrow	5 studies	95% ± 4%	Explore
heart	5 studies	37% ± 20%	Explore
lymph node	4 studies	96% ± 3%	Explore
breast	4 studies	95% ± 2%	Explore
uterus	3 studies	99% ± 1%	Explore
prostate	3 studies	100% ± 0%	Explore
esophagus	3 studies	87% ± 8%	Explore
skin	3 studies	95% ± 3%	Explore
adipose	3 studies	93% ± 5%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
adrenal gland	100%	1069134.27	258 / 258	100%	24165.34	230 / 230
liver	100%	1338870.71	225 / 226	100%	16611.83	404 / 406
prostate	99%	739240.29	242 / 245	99%	17821.91	499 / 502
kidney	99%	2065545.06	88 / 89	99%	20614.24	892 / 901
brain	100%	1324564.06	2631 / 2642	98%	15451.33	692 / 705
pancreas	98%	394550.20	323 / 328	99%	12757.10	176 / 178
stomach	100%	870413.40	358 / 359	98%	17521.57	279 / 286
esophagus	97%	673713.44	1405 / 1445	100%	18844.94	183 / 183
breast	99%	724186.34	455 / 459	97%	11623.23	1088 / 1118
intestine	99%	800299.51	952 / 966	97%	14615.24	513 / 527
skin	98%	461226.74	1764 / 1809	97%	15350.56	459 / 472
bladder	95%	611422.29	20 / 21	96%	14580.66	483 / 504
thymus	93%	487101.94	610 / 653	97%	14247.21	589 / 605
uterus	89%	335025.38	152 / 170	95%	10042.94	435 / 459
lung	87%	306109.81	504 / 578	94%	10554.76	1082 / 1155
ovary	72%	257381.45	130 / 180	100%	13874.77	428 / 430
eye	0%	0	0 / 0	100%	24907.06	80 / 80
muscle	100%	1154483.57	803 / 803	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	36782.30	1 / 1
heart	100%	2013079.22	860 / 861	0%	0	0 / 0
adipose	99%	754749.32	1194 / 1204	0%	0	0 / 0
tonsil	0%	0	0 / 0	98%	7481.36	44 / 45
spleen	92%	338669.54	221 / 241	0%	0	0 / 0
blood vessel	90%	332830.85	1201 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	69%	5386.95	20 / 29
peripheral blood	20%	50057.72	182 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0015990	Biological process	electron transport coupled proton transport
GO_0033762	Biological process	response to glucagon
GO_0031100	Biological process	animal organ regeneration
GO_0045333	Biological process	cellular respiration
GO_0045471	Biological process	response to ethanol
GO_0046686	Biological process	response to cadmium ion
GO_0033590	Biological process	response to cobalamin
GO_0055093	Biological process	response to hyperoxia
GO_0001666	Biological process	response to hypoxia
GO_0046688	Biological process	response to copper ion
GO_0006122	Biological process	mitochondrial electron transport, ubiquinol to cytochrome c
GO_0009410	Biological process	response to xenobiotic stimulus
GO_0009636	Biological process	response to toxic substance
GO_0046689	Biological process	response to mercury ion
GO_0051592	Biological process	response to calcium ion
GO_0005750	Cellular component	mitochondrial respiratory chain complex III
GO_0016020	Cellular component	membrane
GO_0005739	Cellular component	mitochondrion
GO_0005743	Cellular component	mitochondrial inner membrane
GO_0044877	Molecular function	protein-containing complex binding
GO_0046872	Molecular function	metal ion binding
GO_0008121	Molecular function	ubiquinol-cytochrome-c reductase activity

Gene name	MT-CYB
Protein name	Cytochrome b (Complex III subunit 3) (Complex III subunit III) (Cytochrome b-c1 complex subunit 3) (Ubiquinol-cytochrome-c reductase complex cytochrome b subunit)
Synonyms	CYTB MTCYB COB
Description	FUNCTION: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. .
Accessions	ENST00000361789.2 P00156

MT-CYB report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review