Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| GABAergic neuron | 10 studies | 49% ± 20% | |
| interneuron | 7 studies | 60% ± 19% | |
| amacrine cell | 5 studies | 27% ± 9% | |
| type B pancreatic cell | 4 studies | 68% ± 20% | |
| pancreatic A cell | 3 studies | 50% ± 15% | |
| pancreatic D cell | 3 studies | 77% ± 25% | |
| GABAergic interneuron | 3 studies | 55% ± 8% | |
| GABAergic amacrine cell | 3 studies | 44% ± 7% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 88% | 5098.69 | 2331 / 2642 | 67% | 8.49 | 470 / 705 |
| pancreas | 40% | 262.16 | 130 / 328 | 60% | 8.59 | 106 / 178 |
| eye | 0% | 0 | 0 / 0 | 8% | 1.36 | 6 / 80 |
| uterus | 0% | 0 | 0 / 170 | 4% | 0.10 | 20 / 459 |
| skin | 0% | 0.78 | 1 / 1809 | 4% | 0.99 | 20 / 472 |
| intestine | 0% | 0 | 0 / 966 | 3% | 0.44 | 14 / 527 |
| adrenal gland | 0% | 0 | 0 / 258 | 3% | 0.19 | 6 / 230 |
| tonsil | 0% | 0 | 0 / 0 | 2% | 0.04 | 1 / 45 |
| liver | 0% | 0 | 0 / 226 | 2% | 0.12 | 9 / 406 |
| esophagus | 0% | 0 | 0 / 1445 | 2% | 0.02 | 3 / 183 |
| bladder | 0% | 0 | 0 / 21 | 1% | 0.09 | 6 / 504 |
| lung | 0% | 0 | 0 / 578 | 1% | 0.01 | 8 / 1155 |
| stomach | 0% | 0 | 0 / 359 | 0% | 0.01 | 1 / 286 |
| kidney | 0% | 0 | 0 / 89 | 0% | 0.01 | 2 / 901 |
| breast | 0% | 0 | 0 / 459 | 0% | 0.00 | 2 / 1118 |
| muscle | 0% | 0.45 | 1 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| adipose | 0% | 0 | 0 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 0% | 0 | 0 / 1335 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| heart | 0% | 0 | 0 / 861 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ovary | 0% | 0 | 0 / 180 | 0% | 0 | 0 / 430 |
| peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| prostate | 0% | 0 | 0 / 245 | 0% | 0 | 0 / 502 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| thymus | 0% | 0 | 0 / 653 | 0% | 0 | 0 / 605 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_1990416 | Biological process | cellular response to brain-derived neurotrophic factor stimulus |
| GO_0006540 | Biological process | glutamate decarboxylation to succinate |
| GO_0042220 | Biological process | response to cocaine |
| GO_0061771 | Biological process | response to caloric restriction |
| GO_0007268 | Biological process | chemical synaptic transmission |
| GO_0009410 | Biological process | response to xenobiotic stimulus |
| GO_0032570 | Biological process | response to progesterone |
| GO_0009449 | Biological process | gamma-aminobutyric acid biosynthetic process |
| GO_0071456 | Biological process | cellular response to hypoxia |
| GO_0061202 | Cellular component | clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0048471 | Cellular component | perinuclear region of cytoplasm |
| GO_0060077 | Cellular component | inhibitory synapse |
| GO_0030672 | Cellular component | synaptic vesicle membrane |
| GO_0043025 | Cellular component | neuronal cell body |
| GO_0042734 | Cellular component | presynaptic membrane |
| GO_0098982 | Cellular component | GABA-ergic synapse |
| GO_0000139 | Cellular component | Golgi membrane |
| GO_0005829 | Cellular component | cytosol |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0030424 | Cellular component | axon |
| GO_0030170 | Molecular function | pyridoxal phosphate binding |
| GO_0044877 | Molecular function | protein-containing complex binding |
| GO_0016595 | Molecular function | glutamate binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0004351 | Molecular function | glutamate decarboxylase activity |
| Gene name | GAD2 |
| Protein name | glutamate decarboxylase (EC 4.1.1.15) Glutamate decarboxylase 2 (EC 4.1.1.15) (65 kDa glutamic acid decarboxylase) (Glutamate decarboxylase 65 kDa isoform) Glutamate decarboxylase 2 (EC 4.1.1.15) (65 kDa glutamic acid decarboxylase) (GAD-65) (Glutamate decarboxylase 65 kDa isoform) |
| Synonyms | hCG_23434 GAD65 |
| Description | FUNCTION: Catalyzes the production of GABA. . FUNCTION: Catalyzes the production of GABA. . FUNCTION: Catalyzes the production of GABA. . |
| Accessions | ENST00000376261.8 ENST00000648567.1 ENST00000259271.7 A0A3B3IU09 ENST00000428517.2 Q05329 Q5VZ30 Q5VZ31 Q4G154 |
