DGKB | OmnibusX

Name	Number of supported studies	Average coverage
oligodendrocyte precursor cell	11 studies	44% ± 10%	Explore
glutamatergic neuron	11 studies	60% ± 28%	Explore
astrocyte	11 studies	42% ± 18%	Explore
GABAergic neuron	9 studies	54% ± 25%	Explore
smooth muscle cell	7 studies	31% ± 9%	Explore
interneuron	6 studies	51% ± 29%	Explore
neuron	5 studies	45% ± 25%	Explore
pericyte	5 studies	36% ± 17%	Explore
endothelial cell	5 studies	45% ± 10%	Explore
GABAergic interneuron	3 studies	46% ± 14%	Explore
microglial cell	3 studies	47% ± 24%	Explore
retinal bipolar neuron	3 studies	43% ± 18%	Explore
OFF-bipolar cell	3 studies	51% ± 24%	Explore
rod bipolar cell	3 studies	58% ± 31%	Explore

Name	Number of supported studies	Average coverage
brain	13 studies	43% ± 24%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	99%	2541.34	2605 / 2642	96%	12.92	676 / 705
uterus	82%	423.28	140 / 170	6%	0.29	28 / 459
esophagus	61%	605.66	887 / 1445	9%	0.27	17 / 183
intestine	62%	285.88	598 / 966	5%	0.22	25 / 527
adrenal gland	12%	35.27	30 / 258	51%	5.73	118 / 230
bladder	57%	147.90	12 / 21	3%	0.12	14 / 504
stomach	30%	168.94	109 / 359	4%	0.47	11 / 286
kidney	8%	13.70	7 / 89	2%	0.05	22 / 901
pancreas	0%	0.55	1 / 328	8%	0.24	14 / 178
prostate	6%	14.20	14 / 245	2%	0.09	10 / 502
lung	1%	1.89	7 / 578	5%	0.13	57 / 1155
skin	4%	7.89	69 / 1809	2%	0.15	11 / 472
adipose	5%	8.25	62 / 1204	0%	0	0 / 0
muscle	5%	10.47	41 / 803	0%	0	0 / 0
heart	5%	7.79	42 / 861	0%	0	0 / 0
ovary	2%	6.82	4 / 180	2%	0.11	10 / 430
breast	4%	5.61	17 / 459	1%	0.02	7 / 1118
thymus	3%	4.79	20 / 653	0%	0	0 / 605
blood vessel	2%	4.34	30 / 1335	0%	0	0 / 0
liver	0%	0	0 / 226	2%	0.04	9 / 406
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
peripheral blood	0%	0	0 / 929	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
spleen	0%	0	0 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0006654	Biological process	phosphatidic acid biosynthetic process
GO_0046339	Biological process	diacylglycerol metabolic process
GO_0007205	Biological process	protein kinase C-activating G protein-coupled receptor signaling pathway
GO_0035556	Biological process	intracellular signal transduction
GO_0046486	Biological process	glycerolipid metabolic process
GO_0030168	Biological process	platelet activation
GO_0046834	Biological process	lipid phosphorylation
GO_0005886	Cellular component	plasma membrane
GO_0005737	Cellular component	cytoplasm
GO_0045211	Cellular component	postsynaptic membrane
GO_0005509	Molecular function	calcium ion binding
GO_0004143	Molecular function	ATP-dependent diacylglycerol kinase activity
GO_0008289	Molecular function	lipid binding
GO_0005524	Molecular function	ATP binding

Gene name	DGKB
Protein name	Diacylglycerol kinase beta Diacylglycerol kinase (DAG kinase) (EC 2.7.1.107) Diacylglycerol kinase beta (DAG kinase beta) (EC 2.7.1.107) (90 kDa diacylglycerol kinase) (Diglyceride kinase beta) (DGK-beta)
Synonyms	KIAA0718 DAGK2
Description	FUNCTION: Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids . Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes (Probable). Has a higher activity with long-chain diacylglycerols like 1,2-di-(9Z-octadecenoyl)-sn-glycerol compared to 1,2-didecanoyl-sn-glycerol (By similarity). Specifically expressed in brain, it regulates neuron-specific morphological changes including neurite branching and neurite spine formation (By similarity). .; FUNCTION: [Isoform 2]: Does not associate with membranes but has a diacylglycerol kinase activity. .
Accessions	B5MCD5 ENST00000437998.1 Q9Y6T7 ENST00000399322.7 [Q9Y6T7-1] ENST00000407950.5 B7ZL83 B5MBY2 ENST00000403951.6 [Q9Y6T7-1] C9JA18 ENST00000402815.6 ENST00000406247.7 [Q9Y6T7-2]

DGKB report