Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 28 studies | 36% ± 16% | |
pericyte | 20 studies | 37% ± 17% | |
ciliated cell | 16 studies | 35% ± 16% | |
capillary endothelial cell | 11 studies | 24% ± 12% | |
basal cell | 11 studies | 36% ± 21% | |
fibroblast | 11 studies | 24% ± 6% | |
smooth muscle cell | 10 studies | 31% ± 12% | |
glutamatergic neuron | 9 studies | 38% ± 23% | |
epithelial cell | 8 studies | 33% ± 18% | |
oligodendrocyte precursor cell | 8 studies | 24% ± 4% | |
mesothelial cell | 6 studies | 39% ± 10% | |
endothelial cell of lymphatic vessel | 6 studies | 35% ± 12% | |
macrophage | 5 studies | 25% ± 3% | |
GABAergic neuron | 5 studies | 41% ± 18% | |
type I pneumocyte | 5 studies | 23% ± 3% | |
cholangiocyte | 4 studies | 38% ± 22% | |
club cell | 4 studies | 22% ± 3% | |
vein endothelial cell | 4 studies | 35% ± 19% | |
secretory cell | 4 studies | 23% ± 4% | |
endothelial cell of vascular tree | 4 studies | 36% ± 18% | |
interneuron | 4 studies | 24% ± 12% | |
glomerular endothelial cell | 3 studies | 21% ± 4% | |
endothelial cell of artery | 3 studies | 19% ± 4% | |
ON-bipolar cell | 3 studies | 22% ± 5% | |
respiratory goblet cell | 3 studies | 28% ± 11% | |
myeloid cell | 3 studies | 30% ± 16% | |
T cell | 3 studies | 18% ± 2% | |
alveolar macrophage | 3 studies | 29% ± 5% | |
lymphocyte | 3 studies | 25% ± 5% | |
goblet cell | 3 studies | 28% ± 10% | |
transit amplifying cell | 3 studies | 45% ± 34% | |
mucus secreting cell | 3 studies | 26% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 3317.57 | 1443 / 1445 | 100% | 12.32 | 183 / 183 |
bladder | 100% | 4094.29 | 21 / 21 | 98% | 6.70 | 493 / 504 |
intestine | 100% | 2853.28 | 965 / 966 | 97% | 5.85 | 512 / 527 |
lung | 100% | 6084.75 | 578 / 578 | 96% | 5.19 | 1108 / 1155 |
thymus | 100% | 2126.39 | 651 / 653 | 94% | 3.27 | 569 / 605 |
breast | 100% | 3095.16 | 459 / 459 | 93% | 4.42 | 1044 / 1118 |
uterus | 100% | 5610.32 | 170 / 170 | 93% | 4.86 | 427 / 459 |
kidney | 100% | 1974.26 | 89 / 89 | 92% | 6.23 | 829 / 901 |
stomach | 87% | 1796.33 | 313 / 359 | 97% | 6.97 | 278 / 286 |
brain | 90% | 2759.30 | 2366 / 2642 | 88% | 2.27 | 618 / 705 |
skin | 100% | 2524.32 | 1806 / 1809 | 72% | 2.20 | 341 / 472 |
ovary | 100% | 2286.68 | 180 / 180 | 62% | 1.22 | 267 / 430 |
prostate | 100% | 2446.29 | 244 / 245 | 60% | 1.23 | 301 / 502 |
adrenal gland | 75% | 633.48 | 193 / 258 | 68% | 2.40 | 157 / 230 |
pancreas | 39% | 321.09 | 128 / 328 | 98% | 5.92 | 175 / 178 |
ureter | 0% | 0 | 0 / 0 | 100% | 2.52 | 1 / 1 |
blood vessel | 100% | 3843.88 | 1334 / 1335 | 0% | 0 | 0 / 0 |
adipose | 100% | 3069.18 | 1203 / 1204 | 0% | 0 | 0 / 0 |
spleen | 98% | 1379.73 | 237 / 241 | 0% | 0 | 0 / 0 |
heart | 97% | 1484.93 | 838 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 91% | 3.72 | 41 / 45 |
lymph node | 0% | 0 | 0 / 0 | 76% | 2.90 | 22 / 29 |
muscle | 70% | 620.33 | 560 / 803 | 0% | 0 | 0 / 0 |
liver | 21% | 170.01 | 47 / 226 | 37% | 0.85 | 149 / 406 |
peripheral blood | 34% | 1055.47 | 319 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 34% | 0.74 | 27 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006654 | Biological process | phosphatidic acid biosynthetic process |
GO_0046339 | Biological process | diacylglycerol metabolic process |
GO_0046473 | Biological process | phosphatidic acid metabolic process |
GO_0007205 | Biological process | protein kinase C-activating G protein-coupled receptor signaling pathway |
GO_0035556 | Biological process | intracellular signal transduction |
GO_0030168 | Biological process | platelet activation |
GO_0046834 | Biological process | lipid phosphorylation |
GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
GO_0015629 | Cellular component | actin cytoskeleton |
GO_0005768 | Cellular component | endosome |
GO_0005886 | Cellular component | plasma membrane |
GO_0005737 | Cellular component | cytoplasm |
GO_0004143 | Molecular function | ATP-dependent diacylglycerol kinase activity |
GO_0046872 | Molecular function | metal ion binding |
GO_0005524 | Molecular function | ATP binding |
Gene name | DGKH |
Protein name | Diacylglycerol kinase eta (DAG kinase eta) (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) Diacylglycerol kinase (DAG kinase) (EC 2.7.1.107) Diacylglycerol kinase eta |
Synonyms | |
Description | FUNCTION: Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids . Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes (Probable) . Plays a key role in promoting cell growth . Activates the Ras/B-Raf/C-Raf/MEK/ERK signaling pathway induced by EGF . Regulates the recruitment of RAF1 and BRAF from cytoplasm to membranes and their heterodimerization . . |
Accessions | ENST00000261491.9 [Q86XP1-2] A0A0D9SF65 ENST00000626247.2 ENST00000536612.3 [Q86XP1-3] ENST00000379274.6 [Q86XP1-2] ENST00000628433.2 [Q86XP1-5] A0A0D9SFR6 ENST00000337343.9 [Q86XP1-1] ENST00000627777.2 A0A087WZ02 Q86XP1 ENST00000611224.1 |