ENTPD2 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ENTPD2 at tissue level.

III. Associated gene sets

GO_0009134Biological processnucleoside diphosphate catabolic process
GO_0009181Biological processpurine ribonucleoside diphosphate catabolic process
GO_0007186Biological processG protein-coupled receptor signaling pathway
GO_0030168Biological processplatelet activation
GO_0005604Cellular componentbasement membrane
GO_0070062Cellular componentextracellular exosome
GO_0005886Cellular componentplasma membrane
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0004382Molecular functionGDP phosphatase activity
GO_0045134Molecular functionUDP phosphatase activity
GO_0005515Molecular functionprotein binding
GO_0005524Molecular functionATP binding
GO_0017111Molecular functionribonucleoside triphosphate phosphatase activity

IV. Literature review

[source]
Gene nameENTPD2
Protein nameEctonucleoside triphosphate diphosphohydrolase 2 (NTPDase 2) (EC 3.6.1.-) (CD39 antigen-like 1) (Ecto-ATP diphosphohydrolase 2) (Ecto-ATPDase 2) (Ecto-ATPase 2)
SynonymsCD39L1
DescriptionFUNCTION: In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Hydrolyzes ADP only to a marginal extent. The order of activity with different substrates is ATP > GTP > CTP = ITP > UTP >> ADP = UDP.

AccessionsQ9Y5L3
ENST00000355097.7 [Q9Y5L3-1]
ENST00000312665.7 [Q9Y5L3-2]