I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| epithelial cell | 5 studies | 31% ± 13% | |
| ciliated cell | 5 studies | 24% ± 5% | |
| plasma cell | 3 studies | 30% ± 12% | |
| dendritic cell | 3 studies | 19% ± 3% | |
| basal cell | 3 studies | 26% ± 9% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| epithelial cell | 5 studies | 31% ± 13% | |
| ciliated cell | 5 studies | 24% ± 5% | |
| plasma cell | 3 studies | 30% ± 12% | |
| dendritic cell | 3 studies | 19% ± 3% | |
| basal cell | 3 studies | 26% ± 9% |
Insufficient scRNA-seq data for expression of C1GALT1C1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 834.62 | 1445 / 1445 | 100% | 49.11 | 183 / 183 |
| ovary | 100% | 678.38 | 180 / 180 | 100% | 49.45 | 430 / 430 |
| stomach | 100% | 770.05 | 359 / 359 | 100% | 72.57 | 286 / 286 |
| intestine | 100% | 967.53 | 966 / 966 | 100% | 72.93 | 526 / 527 |
| breast | 100% | 1097.76 | 459 / 459 | 100% | 65.44 | 1114 / 1118 |
| uterus | 100% | 875.82 | 170 / 170 | 100% | 53.84 | 457 / 459 |
| liver | 100% | 822.50 | 226 / 226 | 100% | 41.57 | 404 / 406 |
| lung | 99% | 925.72 | 575 / 578 | 100% | 54.74 | 1155 / 1155 |
| bladder | 100% | 836.29 | 21 / 21 | 99% | 57.59 | 501 / 504 |
| prostate | 100% | 799.07 | 245 / 245 | 99% | 63.70 | 499 / 502 |
| pancreas | 99% | 640.54 | 326 / 328 | 100% | 54.16 | 178 / 178 |
| thymus | 100% | 1041.43 | 653 / 653 | 99% | 55.29 | 600 / 605 |
| kidney | 100% | 806.89 | 89 / 89 | 99% | 42.57 | 893 / 901 |
| adrenal gland | 100% | 1929.36 | 258 / 258 | 98% | 54.56 | 226 / 230 |
| brain | 97% | 439.44 | 2553 / 2642 | 100% | 31.55 | 704 / 705 |
| skin | 97% | 1083.63 | 1758 / 1809 | 96% | 36.98 | 453 / 472 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 40.95 | 29 / 29 |
| spleen | 100% | 928.84 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 45.26 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 19.13 | 1 / 1 |
| adipose | 100% | 1087.98 | 1203 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 1107.80 | 1331 / 1335 | 0% | 0 | 0 / 0 |
| heart | 98% | 835.21 | 845 / 861 | 0% | 0 | 0 / 0 |
| muscle | 93% | 320.62 | 746 / 803 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 85% | 19.03 | 68 / 80 |
| peripheral blood | 79% | 762.49 | 731 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0036344 | Biological process | platelet morphogenesis |
| GO_0006493 | Biological process | protein O-linked glycosylation |
| GO_0016267 | Biological process | O-glycan processing, core 1 |
| GO_0030168 | Biological process | platelet activation |
| GO_0000139 | Cellular component | Golgi membrane |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0005515 | Molecular function | protein binding |
| GO_0016263 | Molecular function | glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity |
| Gene name | C1GALT1C1 |
| Protein name | Truncated C1GALT1-specific chaperone 1 C1GALT1-specific chaperone 1 (C38H2-like protein 1) (C38H2-L1) (Core 1 beta1,3-galactosyltransferase 2) (C1Gal-T2) (C1GalT2) (Core 1 beta3-Gal-T2) (Core 1 beta3-galactosyltransferase-specific molecular chaperone) |
| Synonyms | HSPC067 UNQ273/PRO310 MSTP143 COSMC |
| Description | FUNCTION: Probable chaperone required for the generation of 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Probably acts as a specific molecular chaperone assisting the folding/stability of core 1 beta-3-galactosyltransferase (C1GALT1). . |
| Accessions | A0A8F2F415 ENST00000304661.6 Q96EU7 ENST00000371313.2 ENST00000673177.1 ENST00000673568.1 |
