Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| capillary endothelial cell | 8 studies | 30% ± 8% | |
| endothelial cell | 6 studies | 27% ± 6% | |
| endothelial cell of lymphatic vessel | 5 studies | 21% ± 2% |
Insufficient scRNA-seq data for expression of F2RL3 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| thymus | 99% | 3296.38 | 647 / 653 | 89% | 15.01 | 536 / 605 |
| breast | 95% | 2881.71 | 438 / 459 | 80% | 4.75 | 897 / 1118 |
| lung | 98% | 5573.01 | 568 / 578 | 75% | 5.07 | 867 / 1155 |
| pancreas | 69% | 468.27 | 225 / 328 | 98% | 18.59 | 174 / 178 |
| stomach | 73% | 563.51 | 263 / 359 | 85% | 8.13 | 243 / 286 |
| intestine | 72% | 560.71 | 700 / 966 | 81% | 5.81 | 426 / 527 |
| kidney | 78% | 1353.75 | 69 / 89 | 70% | 22.07 | 631 / 901 |
| esophagus | 48% | 289.41 | 693 / 1445 | 82% | 6.81 | 150 / 183 |
| adrenal gland | 45% | 318.45 | 116 / 258 | 80% | 18.86 | 185 / 230 |
| bladder | 52% | 255.48 | 11 / 21 | 66% | 3.86 | 331 / 504 |
| ureter | 0% | 0 | 0 / 0 | 100% | 5.41 | 1 / 1 |
| adipose | 97% | 2913.79 | 1172 / 1204 | 0% | 0 | 0 / 0 |
| uterus | 44% | 204.42 | 74 / 170 | 53% | 2.57 | 241 / 459 |
| prostate | 34% | 179.11 | 84 / 245 | 56% | 3.31 | 281 / 502 |
| ovary | 23% | 84.53 | 41 / 180 | 49% | 2.56 | 210 / 430 |
| skin | 42% | 282.42 | 763 / 1809 | 23% | 1.02 | 109 / 472 |
| liver | 2% | 9.61 | 5 / 226 | 53% | 3.58 | 214 / 406 |
| muscle | 47% | 249.32 | 380 / 803 | 0% | 0 | 0 / 0 |
| heart | 47% | 301.57 | 402 / 861 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 47% | 2.02 | 21 / 45 |
| spleen | 37% | 163.01 | 89 / 241 | 0% | 0 | 0 / 0 |
| blood vessel | 36% | 215.51 | 485 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 34% | 2.22 | 10 / 29 |
| peripheral blood | 15% | 61.63 | 140 / 929 | 0% | 0 | 0 / 0 |
| brain | 2% | 6.00 | 49 / 2642 | 13% | 0.56 | 91 / 705 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0007165 | Biological process | signal transduction |
| GO_0051281 | Biological process | positive regulation of release of sequestered calcium ion into cytosol |
| GO_0035025 | Biological process | positive regulation of Rho protein signal transduction |
| GO_0007200 | Biological process | phospholipase C-activating G protein-coupled receptor signaling pathway |
| GO_0070493 | Biological process | thrombin-activated receptor signaling pathway |
| GO_0007596 | Biological process | blood coagulation |
| GO_0060155 | Biological process | platelet dense granule organization |
| GO_0009611 | Biological process | response to wounding |
| GO_0070527 | Biological process | platelet aggregation |
| GO_0030168 | Biological process | platelet activation |
| GO_0005576 | Cellular component | extracellular region |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0002020 | Molecular function | protease binding |
| GO_0015057 | Molecular function | thrombin-activated receptor activity |
| GO_0004930 | Molecular function | G protein-coupled receptor activity |
| Gene name | F2RL3 |
| Protein name | Proteinase-activated receptor 4 (PAR-4) (Coagulation factor II receptor-like 3) (Thrombin receptor-like 3) F2R like thrombin or trypsin receptor 3 |
| Synonyms | PAR4 |
| Description | FUNCTION: Receptor for activated thrombin or trypsin coupled to G proteins that stimulate phosphoinositide hydrolysis . May play a role in platelets activation . . |
| Accessions | ENST00000599210.1 Q96RI0 M0R0Y0 ENST00000248076.4 |