Name | Number of supported studies | Average coverage | |
---|---|---|---|
classical monocyte | 10 studies | 25% ± 9% | |
non-classical monocyte | 9 studies | 24% ± 8% | |
myeloid cell | 3 studies | 29% ± 9% | |
plasmacytoid dendritic cell | 3 studies | 21% ± 4% |
Insufficient scRNA-seq data for expression of SIRPB1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
lung | 100% | 1061.70 | 578 / 578 | 54% | 1.56 | 629 / 1155 |
kidney | 58% | 80.34 | 52 / 89 | 63% | 2.31 | 572 / 901 |
breast | 76% | 152.79 | 351 / 459 | 29% | 0.66 | 326 / 1118 |
spleen | 100% | 2365.77 | 241 / 241 | 0% | 0 | 0 / 0 |
skin | 51% | 61.80 | 930 / 1809 | 43% | 1.22 | 204 / 472 |
adipose | 90% | 288.14 | 1079 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 86% | 4.15 | 25 / 29 |
peripheral blood | 86% | 12783.20 | 797 / 929 | 0% | 0 | 0 / 0 |
brain | 64% | 143.26 | 1682 / 2642 | 21% | 0.54 | 148 / 705 |
intestine | 58% | 114.63 | 563 / 966 | 26% | 0.67 | 135 / 527 |
stomach | 38% | 63.81 | 138 / 359 | 39% | 1.06 | 111 / 286 |
liver | 67% | 96.45 | 151 / 226 | 9% | 0.16 | 37 / 406 |
bladder | 48% | 82.90 | 10 / 21 | 23% | 0.61 | 118 / 504 |
adrenal gland | 69% | 119.79 | 178 / 258 | 2% | 0.04 | 4 / 230 |
thymus | 50% | 57.43 | 328 / 653 | 17% | 0.28 | 100 / 605 |
pancreas | 24% | 27.12 | 78 / 328 | 41% | 1.09 | 73 / 178 |
uterus | 45% | 55.21 | 77 / 170 | 18% | 0.35 | 81 / 459 |
esophagus | 41% | 49.74 | 597 / 1445 | 20% | 0.48 | 37 / 183 |
ovary | 34% | 40.36 | 62 / 180 | 27% | 0.51 | 116 / 430 |
prostate | 50% | 64.24 | 123 / 245 | 5% | 0.07 | 24 / 502 |
blood vessel | 55% | 92.44 | 728 / 1335 | 0% | 0 | 0 / 0 |
heart | 54% | 71.46 | 462 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 29% | 0.62 | 13 / 45 |
muscle | 23% | 20.56 | 185 / 803 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 9% | 0.13 | 7 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0007165 | Biological process | signal transduction |
GO_0050870 | Biological process | positive regulation of T cell activation |
GO_0050766 | Biological process | positive regulation of phagocytosis |
GO_0007166 | Biological process | cell surface receptor signaling pathway |
GO_0009986 | Cellular component | cell surface |
GO_0030667 | Cellular component | secretory granule membrane |
GO_0005886 | Cellular component | plasma membrane |
GO_0016020 | Cellular component | membrane |
GO_0005515 | Molecular function | protein binding |
Gene name | SIRPB1 |
Protein name | SIRPB1 protein Signal-regulatory protein beta-1 (SIRP-beta-1) (CD172 antigen-like family member B) (CD antigen CD172b) Signal-regulatory protein beta-1 isoform 3 (SIRP-beta-1 isoform 3) Alternative protein SIRPB1 Signal regulatory protein beta 1 |
Synonyms | |
Description | FUNCTION: Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Participates also in the recruitment of tyrosine kinase SYK. Triggers activation of myeloid cells when associated with TYROBP . . FUNCTION: Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. . |
Accessions | H9KV29 H3BRP9 ENST00000279477.11 [Q5TFQ8-1] ENST00000568365.1 [Q5TFQ8-1] H3BSK5 ENST00000566055.5 L8E7G2 ENST00000562014.5 ENST00000381603.7 [O00241-2] H3BTT9 ENST00000563840.1 H3BUW0 ENST00000569629.1 ENST00000262929.9 ENST00000569387.5 ENST00000565087.5 H3BU43 H3BQ21 ENST00000565230.5 ENST00000381605.9 [O00241-1] O00241 ENST00000565076.1 Q5TFQ8 A2RRP5 |