SIRPB1 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of SIRPB1 at tissue level.

III. Associated gene sets

GO_0007165Biological processsignal transduction
GO_0050870Biological processpositive regulation of T cell activation
GO_0050766Biological processpositive regulation of phagocytosis
GO_0007166Biological processcell surface receptor signaling pathway
GO_0009986Cellular componentcell surface
GO_0030667Cellular componentsecretory granule membrane
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameSIRPB1
Protein nameSIRPB1 protein
Signal-regulatory protein beta-1 (SIRP-beta-1) (CD172 antigen-like family member B) (CD antigen CD172b)
Signal-regulatory protein beta-1 isoform 3 (SIRP-beta-1 isoform 3)
Alternative protein SIRPB1
Signal regulatory protein beta 1
Synonyms
DescriptionFUNCTION: Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Participates also in the recruitment of tyrosine kinase SYK. Triggers activation of myeloid cells when associated with TYROBP . .

FUNCTION: Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. .

AccessionsH9KV29
H3BRP9
ENST00000279477.11 [Q5TFQ8-1]
ENST00000568365.1 [Q5TFQ8-1]
H3BSK5
ENST00000566055.5
L8E7G2
ENST00000562014.5
ENST00000381603.7 [O00241-2]
H3BTT9
ENST00000563840.1
H3BUW0
ENST00000569629.1
ENST00000262929.9
ENST00000569387.5
ENST00000565087.5
H3BU43
H3BQ21
ENST00000565230.5
ENST00000381605.9 [O00241-1]
O00241
ENST00000565076.1
Q5TFQ8
A2RRP5