ADGRE5 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
natural killer cell	43 studies	45% ± 14%	Explore
CD8-positive, alpha-beta T cell	32 studies	33% ± 12%	Explore
T cell	30 studies	31% ± 11%	Explore
CD4-positive, alpha-beta T cell	27 studies	28% ± 10%	Explore
macrophage	26 studies	27% ± 9%	Explore
classical monocyte	24 studies	38% ± 15%	Explore
non-classical monocyte	24 studies	58% ± 18%	Explore
monocyte	21 studies	37% ± 14%	Explore
mature NK T cell	21 studies	42% ± 12%	Explore
B cell	17 studies	27% ± 10%	Explore
mast cell	17 studies	28% ± 9%	Explore
CD16-negative, CD56-bright natural killer cell, human	16 studies	51% ± 15%	Explore
CD16-positive, CD56-dim natural killer cell, human	16 studies	51% ± 13%	Explore
gamma-delta T cell	16 studies	40% ± 13%	Explore
regulatory T cell	16 studies	24% ± 6%	Explore
conventional dendritic cell	15 studies	29% ± 15%	Explore
dendritic cell	14 studies	30% ± 14%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	13 studies	25% ± 5%	Explore
memory B cell	13 studies	26% ± 7%	Explore
CD8-positive, alpha-beta memory T cell	12 studies	36% ± 14%	Explore
mucosal invariant T cell	12 studies	40% ± 13%	Explore
plasmacytoid dendritic cell	11 studies	28% ± 7%	Explore
myeloid cell	11 studies	31% ± 11%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	10 studies	31% ± 9%	Explore
effector memory CD8-positive, alpha-beta T cell	10 studies	41% ± 12%	Explore
ciliated cell	9 studies	22% ± 7%	Explore
neutrophil	9 studies	31% ± 9%	Explore
alveolar macrophage	8 studies	37% ± 10%	Explore
innate lymphoid cell	7 studies	42% ± 15%	Explore
CD4-positive, alpha-beta memory T cell	7 studies	30% ± 8%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	6 studies	34% ± 13%	Explore
effector CD8-positive, alpha-beta T cell	6 studies	32% ± 10%	Explore
leukocyte	6 studies	27% ± 6%	Explore
epithelial cell	6 studies	26% ± 5%	Explore
exhausted T cell	5 studies	35% ± 10%	Explore
lymphocyte	5 studies	42% ± 9%	Explore
capillary endothelial cell	5 studies	17% ± 2%	Explore
fibroblast	5 studies	19% ± 1%	Explore
plasma cell	4 studies	24% ± 10%	Explore
endothelial cell	4 studies	19% ± 4%	Explore
deuterosomal cell	4 studies	21% ± 7%	Explore
plasmablast	4 studies	35% ± 13%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	33% ± 4%	Explore
naive B cell	4 studies	22% ± 4%	Explore
mononuclear phagocyte	4 studies	28% ± 7%	Explore
intermediate monocyte	4 studies	59% ± 21%	Explore
CD4-positive helper T cell	4 studies	33% ± 22%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	40% ± 8%	Explore
granulocyte	4 studies	32% ± 10%	Explore
type II pneumocyte	4 studies	22% ± 4%	Explore
T follicular helper cell	4 studies	36% ± 9%	Explore
CD4-positive, alpha-beta cytotoxic T cell	3 studies	18% ± 3%	Explore
hematopoietic precursor cell	3 studies	43% ± 16%	Explore
common myeloid progenitor	3 studies	26% ± 8%	Explore
smooth muscle cell	3 studies	19% ± 3%	Explore
group 3 innate lymphoid cell	3 studies	38% ± 14%	Explore
T-helper 17 cell	3 studies	41% ± 18%	Explore
double negative thymocyte	3 studies	42% ± 13%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
peripheral blood	16 studies	37% ± 9%	Explore
lung	11 studies	25% ± 7%	Explore
intestine	3 studies	22% ± 5%	Explore
lymph node	3 studies	26% ± 3%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
intestine	100%	5531.78	963 / 966	99%	93.22	523 / 527
stomach	98%	3836.79	352 / 359	99%	82.97	284 / 286
lung	100%	10206.16	577 / 578	96%	48.38	1113 / 1155
thymus	97%	2823.76	636 / 653	97%	48.86	586 / 605
uterus	99%	14880.75	169 / 170	92%	49.20	423 / 459
bladder	100%	5127.10	21 / 21	91%	51.79	457 / 504
pancreas	80%	1913.39	261 / 328	94%	69.15	167 / 178
breast	92%	2674.84	424 / 459	76%	18.75	853 / 1118
skin	69%	2708.54	1241 / 1809	99%	75.35	465 / 472
prostate	82%	2110.06	201 / 245	81%	17.36	406 / 502
kidney	72%	2531.49	64 / 89	89%	41.65	798 / 901
esophagus	69%	2694.83	1002 / 1445	88%	45.96	161 / 183
ovary	47%	1278.51	85 / 180	90%	33.04	389 / 430
adrenal gland	91%	2556.84	234 / 258	43%	13.57	99 / 230
peripheral blood	100%	34763.40	929 / 929	0%	0	0 / 0
spleen	100%	18112.65	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	33.73	45 / 45
ureter	0%	0	0 / 0	100%	21.53	1 / 1
blood vessel	100%	12931.45	1333 / 1335	0%	0	0 / 0
adipose	99%	4531.47	1194 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	99%	65.11	79 / 80
liver	40%	871.96	90 / 226	57%	18.73	232 / 406
lymph node	0%	0	0 / 0	97%	88.88	28 / 29
heart	85%	2313.49	730 / 861	0%	0	0 / 0
muscle	79%	1914.14	632 / 803	0%	0	0 / 0
brain	4%	69.62	100 / 2642	49%	15.47	347 / 705
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0