GHRHR report

I. Expression across cell types

Insufficient scRNA-seq data for expression of GHRHR at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of GHRHR at tissue level.

III. Associated gene sets

GO_0060124Biological processpositive regulation of growth hormone secretion
GO_0032869Biological processcellular response to insulin stimulus
GO_0043627Biological processresponse to estrogen
GO_0008340Biological processdetermination of adult lifespan
GO_0030252Biological processgrowth hormone secretion
GO_0032868Biological processresponse to insulin
GO_0051649Biological processestablishment of localization in cell
GO_0060133Biological processsomatotropin secreting cell development
GO_0051384Biological processresponse to glucocorticoid
GO_0043568Biological processpositive regulation of insulin-like growth factor receptor signaling pathway
GO_0007189Biological processadenylate cyclase-activating G protein-coupled receptor signaling pathway
GO_0008284Biological processpositive regulation of cell population proliferation
GO_0007595Biological processlactation
GO_0051246Biological processregulation of protein metabolic process
GO_0048609Biological processmulticellular organismal reproductive process
GO_0033143Biological processregulation of intracellular steroid hormone receptor signaling pathway
GO_0048469Biological processcell maturation
GO_0042445Biological processhormone metabolic process
GO_0040018Biological processpositive regulation of multicellular organism growth
GO_0007166Biological processcell surface receptor signaling pathway
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0005637Cellular componentnuclear inner membrane
GO_0005640Cellular componentnuclear outer membrane
GO_0016363Cellular componentnuclear matrix
GO_0009986Cellular componentcell surface
GO_0005737Cellular componentcytoplasm
GO_0030141Cellular componentsecretory granule
GO_0004930Molecular functionG protein-coupled receptor activity
GO_0017046Molecular functionpeptide hormone binding
GO_0008528Molecular functionG protein-coupled peptide receptor activity
GO_0019838Molecular functiongrowth factor binding
GO_0016520Molecular functiongrowth hormone-releasing hormone receptor activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameGHRHR
Protein nameGrowth hormone releasing hormone receptor variant 2
GHRH receptor splice variant 4 (Growth hormone releasing hormone receptor)
Growth hormone releasing hormone receptor variant 1
Growth hormone releasing hormone receptor
GHRH receptor splice variant 1 (Growth hormone releasing hormone receptor) (Growth hormone releasing hormone receptor, isoform CRA_b)
Growth hormone releasing hormone receptor variant 4
GHRH receptor splice variant 2 (Growth hormone releasing hormone receptor)
Growth hormone-releasing hormone receptor (GHRH receptor) (Growth hormone-releasing factor receptor) (GRF receptor) (GRFR)
GHRH receptor splice variant 3 (Growth hormone releasing hormone receptor)
Synonymstcag7.683
GHRHRpsv
hCG_37325
DescriptionFUNCTION: Receptor for GRF, coupled to G proteins which activate adenylyl cyclase. Stimulates somatotroph cell growth, growth hormone gene transcription and growth hormone secretion.

AccessionsQ02643
A0A1B0H7U2
A0A090N8Y6
Q8N6C4
Q9HB45
ENST00000337750.9
ENST00000396227.6
ENST00000611037.1
ENST00000409904.7
A0A1B0H834
A0A1C6ZRW0
ENST00000409316.5
Q9HB43
Q9HB42
ENST00000326139.7
Q9HB44