CXCR1 | OmnibusX

Name	Number of supported studies	Average coverage
neutrophil	3 studies	21% ± 4%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of CXCR1 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
lung	100%	1135.10	577 / 578	36%	1.42	416 / 1155
spleen	100%	4629.95	241 / 241	0%	0	0 / 0
liver	78%	113.74	177 / 226	10%	0.25	39 / 406
peripheral blood	82%	54301.33	760 / 929	0%	0	0 / 0
kidney	42%	43.45	37 / 89	35%	1.03	311 / 901
stomach	31%	78.28	110 / 359	43%	2.03	124 / 286
adipose	67%	246.38	807 / 1204	0%	0	0 / 0
intestine	24%	34.96	228 / 966	41%	1.88	214 / 527
esophagus	25%	37.47	363 / 1445	35%	1.25	64 / 183
heart	59%	89.14	507 / 861	0%	0	0 / 0
pancreas	9%	10.88	31 / 328	41%	1.31	73 / 178
bladder	24%	180.57	5 / 21	26%	0.98	133 / 504
breast	32%	38.44	146 / 459	16%	0.87	184 / 1118
uterus	20%	39.64	34 / 170	20%	0.92	90 / 459
brain	20%	19.54	521 / 2642	18%	0.59	128 / 705
thymus	34%	36.18	219 / 653	3%	0.09	16 / 605
prostate	23%	23.93	57 / 245	6%	0.12	31 / 502
tonsil	0%	0	0 / 0	29%	1.10	13 / 45
blood vessel	27%	53.70	364 / 1335	0%	0	0 / 0
adrenal gland	12%	9.95	32 / 258	11%	0.31	25 / 230
skin	11%	9.69	198 / 1809	10%	0.31	46 / 472
muscle	19%	15.23	149 / 803	0%	0	0 / 0
ovary	9%	9.29	17 / 180	7%	0.17	28 / 430
lymph node	0%	0	0 / 0	3%	0.13	1 / 29
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0002407	Biological process	dendritic cell chemotaxis
GO_0038112	Biological process	interleukin-8-mediated signaling pathway
GO_0031623	Biological process	receptor internalization
GO_0019722	Biological process	calcium-mediated signaling
GO_0030593	Biological process	neutrophil chemotaxis
GO_0006955	Biological process	immune response
GO_0007186	Biological process	G protein-coupled receptor signaling pathway
GO_0070098	Biological process	chemokine-mediated signaling pathway
GO_0007204	Biological process	positive regulation of cytosolic calcium ion concentration
GO_0007166	Biological process	cell surface receptor signaling pathway
GO_0030667	Cellular component	secretory granule membrane
GO_0009897	Cellular component	external side of plasma membrane
GO_0005886	Cellular component	plasma membrane
GO_0004930	Molecular function	G protein-coupled receptor activity
GO_0016493	Molecular function	C-C chemokine receptor activity
GO_0004950	Molecular function	chemokine receptor activity
GO_0019957	Molecular function	C-C chemokine binding
GO_0019959	Molecular function	interleukin-8 binding
GO_0005515	Molecular function	protein binding
GO_0004918	Molecular function	interleukin-8 receptor activity

Gene name	CXCR1
Protein name	C-X-C chemokine receptor type 1 (CXC-R1) (CXCR-1) (CDw128a) (High affinity interleukin-8 receptor A) (IL-8R A) (IL-8 receptor type 1) (CD antigen CD181)
Synonyms	CMKAR1 IL8RA
Description	FUNCTION: Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor . Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system . .
Accessions	ENST00000295683.3 P25024

CXCR1 report