I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 5 studies | 39% ± 23% | |
| endothelial cell | 3 studies | 33% ± 13% | |
| retinal rod cell | 3 studies | 30% ± 9% | |
| interneuron | 3 studies | 46% ± 18% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 5 studies | 39% ± 23% | |
| endothelial cell | 3 studies | 33% ± 13% | |
| retinal rod cell | 3 studies | 30% ± 9% | |
| interneuron | 3 studies | 46% ± 18% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| kidney | 100% | 844.18 | 89 / 89 | 88% | 20.23 | 793 / 901 |
| pancreas | 97% | 52.95 | 319 / 328 | 10% | 0.54 | 17 / 178 |
| breast | 86% | 135.74 | 395 / 459 | 17% | 1.30 | 191 / 1118 |
| uterus | 79% | 78.37 | 135 / 170 | 16% | 1.33 | 72 / 459 |
| liver | 58% | 48.23 | 131 / 226 | 33% | 3.92 | 132 / 406 |
| adrenal gland | 70% | 40.30 | 181 / 258 | 10% | 0.94 | 23 / 230 |
| brain | 65% | 153.16 | 1726 / 2642 | 11% | 0.44 | 78 / 705 |
| ovary | 4% | 0.96 | 7 / 180 | 72% | 10.60 | 308 / 430 |
| adipose | 67% | 31.20 | 806 / 1204 | 0% | 0 | 0 / 0 |
| spleen | 59% | 18.37 | 143 / 241 | 0% | 0 | 0 / 0 |
| lung | 36% | 7.89 | 208 / 578 | 19% | 1.89 | 220 / 1155 |
| prostate | 45% | 13.74 | 110 / 245 | 6% | 0.25 | 29 / 502 |
| peripheral blood | 39% | 14.38 | 366 / 929 | 0% | 0 | 0 / 0 |
| esophagus | 8% | 2.00 | 121 / 1445 | 29% | 2.52 | 53 / 183 |
| bladder | 14% | 2.71 | 3 / 21 | 22% | 2.02 | 111 / 504 |
| skin | 28% | 8.77 | 514 / 1809 | 2% | 0.07 | 10 / 472 |
| intestine | 23% | 5.45 | 223 / 966 | 6% | 0.39 | 29 / 527 |
| tonsil | 0% | 0 | 0 / 0 | 16% | 0.78 | 7 / 45 |
| thymus | 10% | 1.78 | 63 / 653 | 1% | 0.08 | 4 / 605 |
| blood vessel | 10% | 2.74 | 134 / 1335 | 0% | 0 | 0 / 0 |
| stomach | 3% | 0.43 | 10 / 359 | 6% | 0.48 | 16 / 286 |
| heart | 2% | 0.44 | 18 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 1% | 0.04 | 1 / 80 |
| muscle | 0% | 0.02 | 1 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0007186 | Biological process | G protein-coupled receptor signaling pathway |
| GO_0007188 | Biological process | adenylate cyclase-modulating G protein-coupled receptor signaling pathway |
| GO_0120162 | Biological process | positive regulation of cold-induced thermogenesis |
| GO_0007166 | Biological process | cell surface receptor signaling pathway |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0008528 | Molecular function | G protein-coupled peptide receptor activity |
| GO_0017046 | Molecular function | peptide hormone binding |
| GO_0004991 | Molecular function | parathyroid hormone receptor activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | PTH2R |
| Protein name | Parathyroid hormone 2 receptor Parathyroid hormone 2 receptor (PTH2 receptor) Parathyroid hormone 2 receptor (cDNA FLJ60238, highly similar to Parathyroid hormone receptor) |
| Synonyms | PTHR2 |
| Description | FUNCTION: This is a specific receptor for parathyroid hormone. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. PTH2R may be responsible for PTH effects in a number of physiological systems. It may play a significant role in pancreatic function. PTH2R presence in neurons indicates that it may function as a neurotransmitter receptor (By similarity). . |
| Accessions | B4DFN8 ENST00000272847.7 ENST00000419079.1 H7C0B0 ENST00000617735.4 P49190 |
