TNFRSF25 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of TNFRSF25 at tissue level.

III. Associated gene sets

GO_0007165Biological processsignal transduction
GO_0006915Biological processapoptotic process
GO_0097190Biological processapoptotic signaling pathway
GO_0042981Biological processregulation of apoptotic process
GO_0033209Biological processtumor necrosis factor-mediated signaling pathway
GO_0007166Biological processcell surface receptor signaling pathway
GO_0005829Cellular componentcytosol
GO_0005576Cellular componentextracellular region
GO_0005886Cellular componentplasma membrane
GO_0005031Molecular functiontumor necrosis factor receptor activity
GO_0038023Molecular functionsignaling receptor activity

IV. Literature review

[source]
Gene nameTNFRSF25
Protein nameTumor necrosis factor receptor superfamily member 25 (Apo-3) (Apoptosis-inducing receptor AIR) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death receptor 3) (Lymphocyte-associated receptor of death) (LARD) (Protein WSL) (Protein WSL-1)
TNF receptor superfamily member 25
Tumor necrosis factor receptor superfamily member 25 deletion mutant
SynonymsWSL1
DDR3
UNQ455/PRO779
APO3
DR3
TNFRSF12
WSL
DescriptionFUNCTION: Receptor for TNFSF12/APO3L/TWEAK. Interacts directly with the adapter TRADD. Mediates activation of NF-kappa-B and induces apoptosis. May play a role in regulating lymphocyte homeostasis. .

AccessionsENST00000510563.5 [Q93038-5]
ENST00000485036.5 [Q93038-12]
ENST00000481401.5
ENST00000351748.7 [Q93038-8]
A0A3B3ISD9
ENST00000351959.9 [Q93038-10]
Q93038
A0A0C4DGF3
A5LIN1
K7EJY9
ENST00000502588.5 [Q93038-6]
ENST00000377782.7 [Q93038-11]
ENST00000502730.5 [Q93038-7]
ENST00000647810.1
ENST00000348333.7 [Q93038-9]
ENST00000414040.6 [Q93038-3]
ENST00000356876.8 [Q93038-1]
ENST00000480393.5