Name | Number of supported studies | Average coverage | |
---|---|---|---|
type I pneumocyte | 10 studies | 54% ± 18% | |
retinal cone cell | 7 studies | 58% ± 29% | |
fibroblast | 6 studies | 33% ± 13% | |
oligodendrocyte precursor cell | 6 studies | 35% ± 11% | |
Mueller cell | 5 studies | 65% ± 9% | |
astrocyte | 5 studies | 51% ± 19% | |
type II pneumocyte | 5 studies | 23% ± 4% | |
endothelial cell | 5 studies | 42% ± 23% | |
retinal bipolar neuron | 4 studies | 28% ± 9% | |
retinal pigment epithelial cell | 4 studies | 54% ± 19% | |
glutamatergic neuron | 4 studies | 21% ± 3% | |
kidney loop of Henle epithelial cell | 4 studies | 35% ± 12% | |
pericyte | 3 studies | 37% ± 11% | |
rod bipolar cell | 3 studies | 63% ± 16% | |
GABAergic neuron | 3 studies | 22% ± 3% | |
kidney distal convoluted tubule epithelial cell | 3 studies | 43% ± 16% | |
podocyte | 3 studies | 87% ± 15% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
kidney | 100% | 10029.26 | 89 / 89 | 92% | 7.72 | 828 / 901 |
thymus | 100% | 8094.86 | 653 / 653 | 88% | 12.73 | 532 / 605 |
lung | 97% | 3916.52 | 563 / 578 | 56% | 4.23 | 643 / 1155 |
prostate | 95% | 2392.31 | 232 / 245 | 57% | 1.24 | 286 / 502 |
adrenal gland | 100% | 3992.85 | 258 / 258 | 21% | 0.88 | 48 / 230 |
spleen | 99% | 2724.47 | 238 / 241 | 0% | 0 | 0 / 0 |
muscle | 98% | 4232.32 | 785 / 803 | 0% | 0 | 0 / 0 |
pancreas | 67% | 513.20 | 221 / 328 | 30% | 0.88 | 54 / 178 |
ovary | 83% | 1226.85 | 150 / 180 | 8% | 0.23 | 34 / 430 |
heart | 91% | 1675.07 | 785 / 861 | 0% | 0 | 0 / 0 |
esophagus | 52% | 607.30 | 757 / 1445 | 24% | 0.63 | 44 / 183 |
stomach | 49% | 375.57 | 175 / 359 | 16% | 0.41 | 46 / 286 |
brain | 21% | 143.51 | 558 / 2642 | 41% | 1.38 | 290 / 705 |
blood vessel | 61% | 2015.70 | 817 / 1335 | 0% | 0 | 0 / 0 |
bladder | 43% | 388.19 | 9 / 21 | 17% | 0.69 | 86 / 504 |
uterus | 42% | 408.08 | 72 / 170 | 8% | 0.31 | 37 / 459 |
intestine | 24% | 573.75 | 233 / 966 | 10% | 0.28 | 51 / 527 |
lymph node | 0% | 0 | 0 / 0 | 31% | 1.33 | 9 / 29 |
breast | 18% | 128.85 | 84 / 459 | 9% | 0.18 | 99 / 1118 |
tonsil | 0% | 0 | 0 / 0 | 22% | 0.61 | 10 / 45 |
skin | 9% | 79.53 | 170 / 1809 | 8% | 0.22 | 38 / 472 |
liver | 3% | 17.73 | 7 / 226 | 14% | 0.52 | 57 / 406 |
peripheral blood | 17% | 404.94 | 158 / 929 | 0% | 0 | 0 / 0 |
adipose | 9% | 75.14 | 112 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 3% | 0.07 | 2 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0007605 | Biological process | sensory perception of sound |
GO_0006919 | Biological process | activation of cysteine-type endopeptidase activity involved in apoptotic process |
GO_0008285 | Biological process | negative regulation of cell population proliferation |
GO_0009749 | Biological process | response to glucose |
GO_1905563 | Biological process | negative regulation of vascular endothelial cell proliferation |
GO_0030198 | Biological process | extracellular matrix organization |
GO_0038063 | Biological process | collagen-activated tyrosine kinase receptor signaling pathway |
GO_0007155 | Biological process | cell adhesion |
GO_0032836 | Biological process | glomerular basement membrane development |
GO_0016525 | Biological process | negative regulation of angiogenesis |
GO_0072577 | Biological process | endothelial cell apoptotic process |
GO_0008015 | Biological process | blood circulation |
GO_0007166 | Biological process | cell surface receptor signaling pathway |
GO_0005615 | Cellular component | extracellular space |
GO_0005576 | Cellular component | extracellular region |
GO_0062023 | Cellular component | collagen-containing extracellular matrix |
GO_0005587 | Cellular component | collagen type IV trimer |
GO_0005788 | Cellular component | endoplasmic reticulum lumen |
GO_0005783 | Cellular component | endoplasmic reticulum |
GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
GO_0005604 | Cellular component | basement membrane |
GO_0030020 | Molecular function | extracellular matrix structural constituent conferring tensile strength |
GO_0008191 | Molecular function | metalloendopeptidase inhibitor activity |
GO_0005198 | Molecular function | structural molecule activity |
GO_0005178 | Molecular function | integrin binding |
GO_0005515 | Molecular function | protein binding |
Gene name | COL4A3 |
Protein name | Collagen type IV alpha 3 chain Collagen alpha-3(IV) chain (Goodpasture antigen) [Cleaved into: Tumstatin] Collagen IV alpha 3 chain |
Synonyms | |
Description | FUNCTION: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.; FUNCTION: Tumstatin, a cleavage fragment corresponding to the collagen alpha 3(IV) NC1 domain, possesses both anti-angiogenic and anti-tumor cell activity; these two anti-tumor properties may be regulated via RGD-independent ITGB3-mediated mechanisms. FUNCTION: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. . |
Accessions | ENST00000643388.1 ENST00000469504.2 A0A2R8Y6E5 Q01955 A0A2R8Y2F0 H7BXM4 ENST00000396578.8 [Q01955-1] ENST00000304990.8 Q548X1 |