I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| epithelial cell | 4 studies | 21% ± 5% | |
| neuron | 3 studies | 19% ± 0% | |
| glutamatergic neuron | 3 studies | 31% ± 12% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| epithelial cell | 4 studies | 21% ± 5% | |
| neuron | 3 studies | 19% ± 0% | |
| glutamatergic neuron | 3 studies | 31% ± 12% |
Insufficient scRNA-seq data for expression of ADAP1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| intestine | 97% | 1563.93 | 941 / 966 | 98% | 29.93 | 518 / 527 |
| stomach | 94% | 646.43 | 338 / 359 | 98% | 24.27 | 280 / 286 |
| brain | 100% | 3453.26 | 2640 / 2642 | 83% | 6.69 | 587 / 705 |
| esophagus | 79% | 1159.19 | 1136 / 1445 | 86% | 13.64 | 158 / 183 |
| thymus | 72% | 363.35 | 470 / 653 | 92% | 5.63 | 555 / 605 |
| kidney | 99% | 951.37 | 88 / 89 | 60% | 3.32 | 538 / 901 |
| lung | 81% | 509.81 | 470 / 578 | 77% | 6.16 | 886 / 1155 |
| pancreas | 48% | 215.72 | 156 / 328 | 92% | 18.95 | 164 / 178 |
| bladder | 48% | 329.52 | 10 / 21 | 84% | 12.33 | 422 / 504 |
| ureter | 0% | 0 | 0 / 0 | 100% | 20.48 | 1 / 1 |
| spleen | 98% | 930.53 | 237 / 241 | 0% | 0 | 0 / 0 |
| peripheral blood | 97% | 1731.92 | 900 / 929 | 0% | 0 | 0 / 0 |
| uterus | 21% | 102.04 | 36 / 170 | 68% | 5.32 | 310 / 459 |
| ovary | 1% | 3.96 | 2 / 180 | 81% | 4.33 | 347 / 430 |
| prostate | 54% | 261.22 | 133 / 245 | 23% | 0.82 | 117 / 502 |
| lymph node | 0% | 0 | 0 / 0 | 72% | 3.95 | 21 / 29 |
| breast | 8% | 31.01 | 35 / 459 | 47% | 1.95 | 525 / 1118 |
| eye | 0% | 0 | 0 / 0 | 51% | 2.02 | 41 / 80 |
| tonsil | 0% | 0 | 0 / 0 | 51% | 1.89 | 23 / 45 |
| skin | 5% | 17.70 | 83 / 1809 | 39% | 1.78 | 183 / 472 |
| adrenal gland | 15% | 61.64 | 39 / 258 | 20% | 0.76 | 46 / 230 |
| liver | 5% | 23.60 | 11 / 226 | 24% | 2.52 | 99 / 406 |
| blood vessel | 21% | 91.61 | 278 / 1335 | 0% | 0 | 0 / 0 |
| adipose | 20% | 83.70 | 241 / 1204 | 0% | 0 | 0 / 0 |
| heart | 13% | 48.92 | 110 / 861 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0043087 | Biological process | regulation of GTPase activity |
| GO_0007166 | Biological process | cell surface receptor signaling pathway |
| GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
| GO_0005829 | Cellular component | cytosol |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005634 | Cellular component | nucleus |
| GO_0043533 | Molecular function | inositol 1,3,4,5 tetrakisphosphate binding |
| GO_0005547 | Molecular function | phosphatidylinositol-3,4,5-trisphosphate binding |
| GO_0005096 | Molecular function | GTPase activator activity |
| GO_1902936 | Molecular function | phosphatidylinositol bisphosphate binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0046872 | Molecular function | metal ion binding |
| Gene name | ADAP1 |
| Protein name | ArfGAP with dual PH domains 1 Arf-GAP with dual PH domain-containing protein 1 (Centaurin-alpha-1) (Cnt-a1) (Putative MAPK-activating protein PM25) |
| Synonyms | CENTA1 |
| Description | FUNCTION: GTPase-activating protein for the ADP ribosylation factor family (Probable). Binds phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4). . |
| Accessions | ENST00000435943.1 H7C4B3 ENST00000611167.4 [O75689-3] H0Y7Q1 H7C264 A0A087WTN6 ENST00000617043.4 ENST00000453823.5 ENST00000454383.5 H7C324 ENST00000453175.6 H7BZT6 C9JN36 ENST00000449296.6 [O75689-3] ENST00000446141.5 ENST00000265846.10 [O75689-1] ENST00000437486.5 ENST00000649206.1 O75689 ENST00000539900.5 [O75689-2] A0A3B3ISA7 |
