ADGRB3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_1905806Biological processregulation of synapse pruning
GO_0099558Biological processmaintenance of synapse structure
GO_0016322Biological processneuron remodeling
GO_0048814Biological processregulation of dendrite morphogenesis
GO_0016525Biological processnegative regulation of angiogenesis
GO_0007186Biological processG protein-coupled receptor signaling pathway
GO_0007189Biological processadenylate cyclase-activating G protein-coupled receptor signaling pathway
GO_0007520Biological processmyoblast fusion
GO_0051965Biological processpositive regulation of synapse assembly
GO_0061743Biological processmotor learning
GO_0090128Biological processregulation of synapse maturation
GO_0007166Biological processcell surface receptor signaling pathway
GO_0098839Cellular componentpostsynaptic density membrane
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0098794Cellular componentpostsynapse
GO_0043083Cellular componentsynaptic cleft
GO_0150053Cellular componentcerebellar climbing fiber to Purkinje cell synapse
GO_0004930Molecular functionG protein-coupled receptor activity
GO_0005096Molecular functionGTPase activator activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameADGRB3
Protein nameAdhesion G protein-coupled receptor B3 (Brain-specific angiogenesis inhibitor 3)
Adhesion G protein-coupled receptor B3
SynonymsKIAA0550
BAI3
DescriptionFUNCTION: Receptor that plays a role in the regulation of synaptogenesis and dendritic spine formation at least partly via interaction with ELMO1 and RAC1 activity (By similarity). Promotes myoblast fusion through ELMO/DOCK1 . .

AccessionsENST00000370598.6 [O60242-1]
S4R307
J3KMY8
A0A804HJR2
S4R3D0
O60242
ENST00000603207.1
ENST00000604969.1
ENST00000546190.5 [O60242-1]
ENST00000238918.12
ENST00000684661.1