I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| B cell | 25 studies | 27% ± 6% | |
| memory B cell | 19 studies | 35% ± 9% | |
| plasma cell | 12 studies | 34% ± 13% | |
| plasmablast | 7 studies | 46% ± 21% | |
| IgA plasma cell | 4 studies | 22% ± 8% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| B cell | 25 studies | 27% ± 6% | |
| memory B cell | 19 studies | 35% ± 9% | |
| plasma cell | 12 studies | 34% ± 13% | |
| plasmablast | 7 studies | 46% ± 21% | |
| IgA plasma cell | 4 studies | 22% ± 8% |
Insufficient scRNA-seq data for expression of TNFRSF13B at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 78% | 51.00 | 451 / 578 | 33% | 0.96 | 379 / 1155 |
| spleen | 100% | 2032.49 | 241 / 241 | 0% | 0 | 0 / 0 |
| peripheral blood | 96% | 3023.57 | 888 / 929 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 90% | 79.91 | 26 / 29 |
| stomach | 62% | 44.77 | 221 / 359 | 21% | 0.73 | 59 / 286 |
| intestine | 54% | 318.75 | 524 / 966 | 12% | 0.96 | 65 / 527 |
| tonsil | 0% | 0 | 0 / 0 | 51% | 2.25 | 23 / 45 |
| breast | 30% | 15.88 | 136 / 459 | 16% | 0.72 | 180 / 1118 |
| esophagus | 24% | 18.53 | 347 / 1445 | 15% | 0.48 | 27 / 183 |
| bladder | 24% | 23.67 | 5 / 21 | 11% | 0.42 | 56 / 504 |
| thymus | 20% | 35.73 | 129 / 653 | 15% | 0.55 | 89 / 605 |
| prostate | 25% | 14.44 | 62 / 245 | 7% | 0.17 | 36 / 502 |
| liver | 23% | 6.23 | 52 / 226 | 4% | 0.26 | 15 / 406 |
| kidney | 21% | 19.16 | 19 / 89 | 4% | 0.10 | 36 / 901 |
| uterus | 8% | 2.73 | 13 / 170 | 16% | 0.37 | 75 / 459 |
| skin | 2% | 0.50 | 31 / 1809 | 21% | 1.00 | 100 / 472 |
| pancreas | 1% | 0.37 | 4 / 328 | 19% | 0.88 | 33 / 178 |
| adipose | 15% | 8.36 | 178 / 1204 | 0% | 0 | 0 / 0 |
| ovary | 9% | 2.48 | 16 / 180 | 1% | 0.02 | 6 / 430 |
| brain | 5% | 1.05 | 124 / 2642 | 1% | 0.23 | 4 / 705 |
| blood vessel | 5% | 5.85 | 66 / 1335 | 0% | 0 | 0 / 0 |
| adrenal gland | 3% | 0.59 | 7 / 258 | 1% | 0.02 | 3 / 230 |
| eye | 0% | 0 | 0 / 0 | 4% | 0.16 | 3 / 80 |
| heart | 3% | 2.20 | 25 / 861 | 0% | 0 | 0 / 0 |
| muscle | 1% | 0.11 | 5 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0002250 | Biological process | adaptive immune response |
| GO_0002244 | Biological process | hematopoietic progenitor cell differentiation |
| GO_0001782 | Biological process | B cell homeostasis |
| GO_0030889 | Biological process | negative regulation of B cell proliferation |
| GO_0007166 | Biological process | cell surface receptor signaling pathway |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0038023 | Molecular function | signaling receptor activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | TNFRSF13B |
| Protein name | Tumor necrosis factor receptor superfamily member 13B TACI (Tumor necrosis factor receptor superfamily, member 13B) Tumor necrosis factor receptor superfamily member 13B (Transmembrane activator and CAML interactor) (CD antigen CD267) TNF receptor superfamily member 13B |
| Synonyms | TACI hCG_28297 |
| Description | FUNCTION: Receptor for TNFSF13/APRIL and TNFSF13B/TALL1/BAFF/BLYS that binds both ligands with similar high affinity. Mediates calcineurin-dependent activation of NF-AT, as well as activation of NF-kappa-B and AP-1. Involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. . |
| Accessions | ENST00000261652.7 [O14836-1] ENST00000579315.5 Q4ACX1 ENST00000584950.5 A0A141AWZ3 J3QR67 ENST00000583789.1 [O14836-2] E7ER05 O14836 |
