Name | Number of supported studies | Average coverage | |
---|---|---|---|
non-classical monocyte | 23 studies | 39% ± 13% | |
mast cell | 21 studies | 27% ± 12% | |
classical monocyte | 16 studies | 24% ± 9% | |
monocyte | 15 studies | 28% ± 10% | |
macrophage | 9 studies | 21% ± 6% | |
conventional dendritic cell | 5 studies | 23% ± 6% | |
myeloid cell | 5 studies | 27% ± 6% | |
dendritic cell | 5 studies | 26% ± 14% | |
mononuclear phagocyte | 4 studies | 21% ± 4% | |
microglial cell | 4 studies | 20% ± 5% | |
neutrophil | 3 studies | 29% ± 4% | |
intermediate monocyte | 3 studies | 49% ± 5% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
peripheral blood | 3 studies | 18% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
lung | 100% | 1252.07 | 577 / 578 | 91% | 4.45 | 1048 / 1155 |
skin | 89% | 354.57 | 1618 / 1809 | 88% | 4.61 | 413 / 472 |
breast | 87% | 393.21 | 400 / 459 | 76% | 2.21 | 855 / 1118 |
bladder | 86% | 244.14 | 18 / 21 | 77% | 3.10 | 387 / 504 |
stomach | 75% | 173.87 | 269 / 359 | 83% | 3.23 | 238 / 286 |
esophagus | 68% | 146.10 | 979 / 1445 | 87% | 3.58 | 160 / 183 |
intestine | 74% | 218.76 | 712 / 966 | 79% | 2.57 | 415 / 527 |
kidney | 76% | 333.06 | 68 / 89 | 72% | 3.48 | 653 / 901 |
prostate | 96% | 383.81 | 234 / 245 | 37% | 0.68 | 186 / 502 |
uterus | 63% | 134.42 | 107 / 170 | 66% | 2.58 | 303 / 459 |
adrenal gland | 96% | 422.27 | 247 / 258 | 19% | 0.40 | 44 / 230 |
pancreas | 29% | 69.10 | 94 / 328 | 76% | 2.34 | 136 / 178 |
spleen | 100% | 4198.24 | 241 / 241 | 0% | 0 | 0 / 0 |
peripheral blood | 100% | 7956.15 | 926 / 929 | 0% | 0 | 0 / 0 |
thymus | 59% | 120.99 | 383 / 653 | 40% | 0.89 | 242 / 605 |
eye | 0% | 0 | 0 / 0 | 93% | 4.54 | 74 / 80 |
adipose | 92% | 409.02 | 1112 / 1204 | 0% | 0 | 0 / 0 |
brain | 36% | 93.30 | 938 / 2642 | 51% | 1.88 | 361 / 705 |
liver | 55% | 145.19 | 125 / 226 | 18% | 0.38 | 72 / 406 |
lymph node | 0% | 0 | 0 / 0 | 72% | 6.20 | 21 / 29 |
tonsil | 0% | 0 | 0 / 0 | 71% | 2.42 | 32 / 45 |
ovary | 13% | 22.71 | 24 / 180 | 47% | 1.10 | 203 / 430 |
blood vessel | 59% | 180.20 | 784 / 1335 | 0% | 0 | 0 / 0 |
heart | 35% | 72.11 | 305 / 861 | 0% | 0 | 0 / 0 |
muscle | 6% | 8.55 | 47 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0043304 | Biological process | regulation of mast cell degranulation |
GO_0071621 | Biological process | granulocyte chemotaxis |
GO_0007186 | Biological process | G protein-coupled receptor signaling pathway |
GO_0007189 | Biological process | adenylate cyclase-activating G protein-coupled receptor signaling pathway |
GO_0006954 | Biological process | inflammatory response |
GO_0007155 | Biological process | cell adhesion |
GO_0016477 | Biological process | cell migration |
GO_0007166 | Biological process | cell surface receptor signaling pathway |
GO_0032587 | Cellular component | ruffle membrane |
GO_0031256 | Cellular component | leading edge membrane |
GO_0005886 | Cellular component | plasma membrane |
GO_0016020 | Cellular component | membrane |
GO_0035374 | Molecular function | chondroitin sulfate binding |
GO_0004930 | Molecular function | G protein-coupled receptor activity |
GO_0005509 | Molecular function | calcium ion binding |
GO_0005515 | Molecular function | protein binding |
Gene name | ADGRE2 |
Protein name | EMR2 protein Adhesion G protein-coupled receptor E2 (cDNA FLJ60183, highly similar to Homo sapiens egf-like module containing, mucin-like, hormone receptor-like 2, transcript variant 6, mRNA) Adhesion G protein-coupled receptor E2 (EGF-like module receptor 2) (EGF-like module-containing mucin-like hormone receptor-like 2) (CD antigen CD312) Egf-like module containing, mucin-like, hormone receptor-like 2 Adhesion G protein-coupled receptor E2 |
Synonyms | EMR2 |
Description | FUNCTION: Cell surface receptor that binds to the chondroitin sulfate moiety of glycosaminoglycan chains and promotes cell attachment. Promotes granulocyte chemotaxis, degranulation and adhesion. In macrophages, promotes the release of inflammatory cytokines, including IL8 and TNF. Signals probably through G-proteins. Is a regulator of mast cell degranulation . . |
Accessions | ENST00000392965.7 [Q9UHX3-6] ENST00000595839.5 [Q9UHX3-5] ENST00000595208.5 ENST00000392962.3 ENST00000596991.6 [Q9UHX3-2] ENST00000315576.8 [Q9UHX3-1] M0QY55 M0R0K5 Q7Z618 A0JNV7 B4DWB8 ENST00000594076.5 [Q9UHX3-4] ENST00000594294.5 [Q9UHX3-3] ENST00000601345.5 Q9UHX3 |