CYSLTR1 | OmnibusX

Name	Number of supported studies	Average coverage
B cell	12 studies	19% ± 5%	Explore
plasmacytoid dendritic cell	9 studies	33% ± 15%	Explore
memory B cell	6 studies	20% ± 3%	Explore
non-classical monocyte	4 studies	23% ± 6%	Explore
endothelial cell	3 studies	18% ± 2%	Explore
microglial cell	3 studies	20% ± 3%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of CYSLTR1 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
breast	97%	306.29	447 / 459	86%	4.10	962 / 1118
lung	95%	203.22	551 / 578	77%	3.27	891 / 1155
thymus	93%	238.51	610 / 653	73%	1.57	442 / 605
prostate	89%	126.53	218 / 245	71%	1.81	355 / 502
esophagus	96%	1109.03	1380 / 1445	48%	1.86	87 / 183
stomach	84%	218.21	303 / 359	51%	1.33	147 / 286
kidney	65%	80.51	58 / 89	61%	2.29	547 / 901
intestine	89%	195.16	858 / 966	36%	0.83	192 / 527
bladder	76%	114.90	16 / 21	36%	1.07	181 / 504
uterus	66%	73.45	113 / 170	40%	1.19	183 / 459
spleen	100%	669.66	241 / 241	0%	0	0 / 0
pancreas	34%	28.37	111 / 328	65%	2.14	115 / 178
adipose	98%	343.95	1175 / 1204	0%	0	0 / 0
peripheral blood	94%	385.66	876 / 929	0%	0	0 / 0
skin	54%	63.71	979 / 1809	37%	0.93	176 / 472
adrenal gland	65%	67.01	168 / 258	20%	0.36	47 / 230
lymph node	0%	0	0 / 0	83%	4.84	24 / 29
brain	25%	22.05	652 / 2642	50%	0.97	350 / 705
blood vessel	74%	144.35	982 / 1335	0%	0	0 / 0
tonsil	0%	0	0 / 0	62%	1.62	28 / 45
ovary	10%	13.11	18 / 180	33%	1.04	140 / 430
heart	29%	25.90	250 / 861	0%	0	0 / 0
liver	5%	3.49	11 / 226	15%	0.27	61 / 406
muscle	17%	20.90	136 / 803	0%	0	0 / 0
eye	0%	0	0 / 0	3%	0.04	2 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0007218	Biological process	neuropeptide signaling pathway
GO_0045766	Biological process	positive regulation of angiogenesis
GO_0060252	Biological process	positive regulation of glial cell proliferation
GO_0045907	Biological process	positive regulation of vasoconstriction
GO_0006935	Biological process	chemotaxis
GO_0002437	Biological process	inflammatory response to antigenic stimulus
GO_0051649	Biological process	establishment of localization in cell
GO_0007585	Biological process	respiratory gaseous exchange by respiratory system
GO_0007204	Biological process	positive regulation of cytosolic calcium ion concentration
GO_0061737	Biological process	leukotriene signaling pathway
GO_0006816	Biological process	calcium ion transport
GO_0006952	Biological process	defense response
GO_0007166	Biological process	cell surface receptor signaling pathway
GO_0071456	Biological process	cellular response to hypoxia
GO_0005886	Cellular component	plasma membrane
GO_0016020	Cellular component	membrane
GO_0004974	Molecular function	leukotriene receptor activity
GO_0001631	Molecular function	cysteinyl leukotriene receptor activity
GO_0008528	Molecular function	G protein-coupled peptide receptor activity

Gene name	CYSLTR1
Protein name	Cysteinyl leukotriene receptor 1 (CysLTR1) (Cysteinyl leukotriene D4 receptor) (LTD4 receptor) (G-protein coupled receptor HG55) (HMTMF81)
Synonyms	CYSLT1
Description	FUNCTION: Receptor for cysteinyl leukotrienes mediating bronchoconstriction of individuals with and without asthma. Stimulation by LTD4 results in the contraction and proliferation of smooth muscle, edema, eosinophil migration and damage to the mucus layer in the lung. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTD4 >> LTE4 = LTC4 >> LTB4.
Accessions	ENST00000614798.1 Q9Y271 ENST00000373304.4

CYSLTR1 report