I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| macrophage | 10 studies | 21% ± 6% | |
| plasmacytoid dendritic cell | 7 studies | 26% ± 7% | |
| microglial cell | 5 studies | 29% ± 8% | |
| conventional dendritic cell | 3 studies | 28% ± 9% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| macrophage | 10 studies | 21% ± 6% | |
| plasmacytoid dendritic cell | 7 studies | 26% ± 7% | |
| microglial cell | 5 studies | 29% ± 8% | |
| conventional dendritic cell | 3 studies | 28% ± 9% |
Insufficient scRNA-seq data for expression of MILR1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| breast | 95% | 201.12 | 436 / 459 | 96% | 8.51 | 1074 / 1118 |
| lung | 100% | 499.91 | 576 / 578 | 90% | 9.91 | 1036 / 1155 |
| thymus | 88% | 141.38 | 574 / 653 | 91% | 8.74 | 550 / 605 |
| bladder | 95% | 172.71 | 20 / 21 | 71% | 6.23 | 359 / 504 |
| ovary | 81% | 128.33 | 145 / 180 | 84% | 7.96 | 363 / 430 |
| kidney | 67% | 104.00 | 60 / 89 | 86% | 8.15 | 779 / 901 |
| intestine | 83% | 157.62 | 801 / 966 | 62% | 3.88 | 329 / 527 |
| uterus | 69% | 85.05 | 118 / 170 | 75% | 4.99 | 345 / 459 |
| brain | 50% | 83.98 | 1314 / 2642 | 93% | 11.10 | 655 / 705 |
| adrenal gland | 98% | 236.07 | 254 / 258 | 44% | 2.20 | 101 / 230 |
| esophagus | 72% | 109.24 | 1043 / 1445 | 66% | 3.43 | 120 / 183 |
| skin | 50% | 180.51 | 913 / 1809 | 85% | 9.55 | 399 / 472 |
| prostate | 83% | 141.55 | 203 / 245 | 46% | 1.65 | 231 / 502 |
| pancreas | 30% | 35.52 | 97 / 328 | 90% | 11.81 | 161 / 178 |
| stomach | 48% | 60.90 | 171 / 359 | 71% | 5.07 | 203 / 286 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 26.45 | 29 / 29 |
| spleen | 100% | 821.49 | 241 / 241 | 0% | 0 | 0 / 0 |
| adipose | 99% | 345.34 | 1187 / 1204 | 0% | 0 | 0 / 0 |
| peripheral blood | 97% | 869.81 | 897 / 929 | 0% | 0 | 0 / 0 |
| blood vessel | 94% | 280.28 | 1261 / 1335 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 84% | 5.45 | 38 / 45 |
| liver | 26% | 26.05 | 59 / 226 | 47% | 2.23 | 191 / 406 |
| heart | 72% | 123.94 | 623 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 20% | 0.69 | 16 / 80 |
| muscle | 13% | 11.66 | 104 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0043303 | Biological process | mast cell degranulation |
| GO_0006955 | Biological process | immune response |
| GO_0033004 | Biological process | negative regulation of mast cell activation |
| GO_0007166 | Biological process | cell surface receptor signaling pathway |
| GO_0009897 | Cellular component | external side of plasma membrane |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0004888 | Molecular function | transmembrane signaling receptor activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | MILR1 |
| Protein name | Mast cell immunoglobulin like receptor 1 Allergin-1 (Allergy inhibitory receptor 1) (Mast cell antigen 32) (MCA-32) (Mast cell immunoglobulin-like receptor 1) |
| Synonyms | MCA32 C17orf60 |
| Description | FUNCTION: Immunoglobulin-like receptor which plays an inhibitory role in degranulation of mast cells. Negatively regulates IgE-mediated mast cell activation and suppresses the type I immediate hypersensitivity reaction (By similarity). . |
| Accessions | ENST00000615220.4 [Q7Z6M3-1] ENST00000616498.4 [Q7Z6M3-2] A0A087WVL4 ENST00000605096.1 ENST00000612535.4 [Q7Z6M3-3] S4R3N6 Q7Z6M3 ENST00000620304.4 ENST00000619286.5 [Q7Z6M3-1] ENST00000617071.4 |
