FCGR2C report

I. Expression across cell types

Insufficient scRNA-seq data for expression of FCGR2C at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of FCGR2C at tissue level.

III. Associated gene sets

GO_0006955Biological processimmune response
GO_0050766Biological processpositive regulation of phagocytosis
GO_0001788Biological processantibody-dependent cellular cytotoxicity
GO_0032760Biological processpositive regulation of tumor necrosis factor production
GO_0038094Biological processFc-gamma receptor signaling pathway
GO_0007166Biological processcell surface receptor signaling pathway
GO_0009897Cellular componentexternal side of plasma membrane
GO_0016020Cellular componentmembrane
GO_0005737Cellular componentcytoplasm
GO_0004888Molecular functiontransmembrane signaling receptor activity
GO_0019864Molecular functionIgG binding
GO_0019770Molecular functionIgG receptor activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameFCGR2C
Protein nameLow affinity immunoglobulin gamma Fc region receptor II-c (IgG Fc receptor II-c) (CDw32) (Fc-gamma RII-c) (Fc-gamma-RIIc) (FcRII-c) (CD antigen CD32)
SynonymsIGFR2
FCG2
CD32
DescriptionFUNCTION: Receptor for the Fc region of complexed immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells.

AccessionsP31995