Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| pericyte | 14 studies | 25% ± 10% | |
| epithelial cell of proximal tubule | 7 studies | 42% ± 25% | |
| smooth muscle cell | 6 studies | 24% ± 7% | |
| podocyte | 5 studies | 53% ± 21% | |
| kidney loop of Henle epithelial cell | 5 studies | 38% ± 8% | |
| kidney distal convoluted tubule epithelial cell | 4 studies | 35% ± 13% | |
| endothelial cell | 4 studies | 31% ± 7% | |
| fibroblast | 3 studies | 38% ± 29% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| kidney | 5 studies | 32% ± 11% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 100% | 1270.64 | 2633 / 2642 | 99% | 13.79 | 699 / 705 |
| kidney | 100% | 26724.81 | 89 / 89 | 89% | 52.70 | 802 / 901 |
| adrenal gland | 100% | 4255.37 | 258 / 258 | 61% | 4.13 | 140 / 230 |
| breast | 100% | 1435.54 | 458 / 459 | 43% | 2.26 | 484 / 1118 |
| liver | 97% | 2802.33 | 219 / 226 | 42% | 3.14 | 171 / 406 |
| lung | 99% | 2012.32 | 573 / 578 | 34% | 1.62 | 391 / 1155 |
| prostate | 93% | 879.37 | 229 / 245 | 36% | 1.28 | 179 / 502 |
| ovary | 100% | 1475.84 | 180 / 180 | 27% | 1.97 | 117 / 430 |
| uterus | 99% | 1917.56 | 169 / 170 | 27% | 6.38 | 124 / 459 |
| pancreas | 52% | 220.46 | 171 / 328 | 69% | 3.41 | 123 / 178 |
| bladder | 100% | 875.95 | 21 / 21 | 16% | 0.71 | 79 / 504 |
| thymus | 85% | 520.17 | 555 / 653 | 20% | 0.92 | 121 / 605 |
| intestine | 95% | 704.45 | 918 / 966 | 9% | 0.48 | 48 / 527 |
| adipose | 100% | 2040.23 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| spleen | 100% | 3727.15 | 241 / 241 | 0% | 0 | 0 / 0 |
| blood vessel | 99% | 1194.90 | 1318 / 1335 | 0% | 0 | 0 / 0 |
| heart | 98% | 1108.43 | 845 / 861 | 0% | 0 | 0 / 0 |
| skin | 77% | 528.11 | 1393 / 1809 | 19% | 0.98 | 89 / 472 |
| esophagus | 74% | 950.49 | 1074 / 1445 | 7% | 0.23 | 12 / 183 |
| stomach | 70% | 397.74 | 252 / 359 | 10% | 0.39 | 28 / 286 |
| muscle | 59% | 274.95 | 477 / 803 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 38% | 1.13 | 11 / 29 |
| eye | 0% | 0 | 0 / 0 | 28% | 1.76 | 22 / 80 |
| tonsil | 0% | 0 | 0 / 0 | 16% | 0.46 | 7 / 45 |
| peripheral blood | 0% | 1.25 | 2 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0008285 | Biological process | negative regulation of cell population proliferation |
| GO_0007188 | Biological process | adenylate cyclase-modulating G protein-coupled receptor signaling pathway |
| GO_0008283 | Biological process | cell population proliferation |
| GO_0007200 | Biological process | phospholipase C-activating G protein-coupled receptor signaling pathway |
| GO_0001701 | Biological process | in utero embryonic development |
| GO_0002062 | Biological process | chondrocyte differentiation |
| GO_0060732 | Biological process | positive regulation of inositol phosphate biosynthetic process |
| GO_0006874 | Biological process | intracellular calcium ion homeostasis |
| GO_0007186 | Biological process | G protein-coupled receptor signaling pathway |
| GO_0030282 | Biological process | bone mineralization |
| GO_0045453 | Biological process | bone resorption |
| GO_0007189 | Biological process | adenylate cyclase-activating G protein-coupled receptor signaling pathway |
| GO_0007187 | Biological process | G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger |
| GO_0001501 | Biological process | skeletal system development |
| GO_0008284 | Biological process | positive regulation of cell population proliferation |
| GO_0048469 | Biological process | cell maturation |
| GO_0002076 | Biological process | osteoblast development |
| GO_0007166 | Biological process | cell surface receptor signaling pathway |
| GO_0016324 | Cellular component | apical plasma membrane |
| GO_0043235 | Cellular component | receptor complex |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0016323 | Cellular component | basolateral plasma membrane |
| GO_0005634 | Cellular component | nucleus |
| GO_0042803 | Molecular function | protein homodimerization activity |
| GO_0004991 | Molecular function | parathyroid hormone receptor activity |
| GO_0017046 | Molecular function | peptide hormone binding |
| GO_0008528 | Molecular function | G protein-coupled peptide receptor activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | PTH1R |
| Protein name | Parathyroid hormone/parathyroid hormone-related peptide receptor (PTH/PTHrP type I receptor) (PTH/PTHr receptor) (Parathyroid hormone 1 receptor) (PTH1 receptor) Parathyroid hormone 1 receptor Parathyroid hormone/parathyroid hormone-related peptide receptor (PTH/PTHrP type I receptor) (Parathyroid hormone 1 receptor) |
| Synonyms | PTHR1 PTHR |
| Description | FUNCTION: Receptor for parathyroid hormone and for parathyroid hormone-related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. . |
| Accessions | ENST00000422115.2 ENST00000427125.6 E7EWE7 ENST00000430002.6 F2Z314 ENST00000428220.1 ENST00000449590.6 Q0VGD7 Q03431 H7C0Q3 ENST00000313049.9 ENST00000418619.5 |
