CLEC1B | OmnibusX

Name	Number of supported studies	Average coverage
platelet	9 studies	45% ± 16%	Explore
megakaryocyte	5 studies	78% ± 9%	Explore
endothelial cell of sinusoid	3 studies	37% ± 7%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of CLEC1B at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
liver	98%	581.56	221 / 226	5%	0.16	22 / 406
spleen	100%	155.49	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	2.87	1 / 1
lung	98%	126.21	566 / 578	2%	0.04	20 / 1155
peripheral blood	81%	205.95	750 / 929	0%	0	0 / 0
adrenal gland	63%	18.32	162 / 258	0%	0	0 / 230
adipose	45%	11.01	541 / 1204	0%	0	0 / 0
heart	18%	2.90	154 / 861	0%	0	0 / 0
breast	17%	2.76	79 / 459	1%	0.01	6 / 1118
intestine	17%	2.75	164 / 966	0%	0.00	1 / 527
kidney	12%	3.17	11 / 89	1%	0.02	8 / 901
stomach	12%	1.63	43 / 359	1%	0.02	3 / 286
esophagus	11%	1.73	153 / 1445	2%	0.04	3 / 183
skin	11%	1.67	190 / 1809	1%	0.02	4 / 472
thymus	10%	1.43	68 / 653	0%	0	0 / 605
blood vessel	10%	1.82	133 / 1335	0%	0	0 / 0
bladder	5%	0.52	1 / 21	4%	0.09	21 / 504
uterus	8%	1.14	14 / 170	1%	0.01	3 / 459
prostate	9%	1.23	21 / 245	0%	0	0 / 502
pancreas	4%	0.72	14 / 328	2%	0.08	4 / 178
ovary	4%	0.77	8 / 180	0%	0.01	2 / 430
muscle	2%	0.25	15 / 803	0%	0	0 / 0
brain	1%	0.20	30 / 2642	0%	0	0 / 705
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45

GO_0007165	Biological process	signal transduction
GO_0030220	Biological process	platelet formation
GO_0006952	Biological process	defense response
GO_0007166	Biological process	cell surface receptor signaling pathway
GO_0009986	Cellular component	cell surface
GO_0005886	Cellular component	plasma membrane
GO_0004888	Molecular function	transmembrane signaling receptor activity
GO_0030246	Molecular function	carbohydrate binding
GO_0005515	Molecular function	protein binding

Gene name	CLEC1B
Protein name	C-type lectin domain family 1 member B C-type lectin domain family 1 member B (C-type lectin-like receptor 2) (CLEC-2)
Synonyms	CLEC2 UNQ721/PRO1384
Description	FUNCTION: C-type lectin-like receptor that functions as a platelet receptor for the lymphatic endothelial marker, PDPN . After ligand activation, signals via sequential activation of SRC and SYK tyrosine kinases leading to activation of PLCG2 . .; FUNCTION: (Microbial infection) Acts as a receptor for the platelet-aggregating snake venom protein rhodocytin. Rhodocytin binding leads to tyrosine phosphorylation and this promotes the binding of spleen tyrosine kinase (SYK) and initiation of downstream tyrosine phosphorylation events and activation of PLCG2 . .; FUNCTION: (Microbial infection) Acts as an attachment factor for Human immunodeficiency virus type 1 (HIV-1) and facilitates its capture by platelets . .
Accessions	ENST00000298527.11 [Q9P126-1] ENST00000428126.6 [Q9P126-2] ENST00000398937.6 H7BYT7 ENST00000348658.4 [Q9P126-2] Q9P126

CLEC1B report