I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| ciliated cell | 10 studies | 28% ± 10% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| ciliated cell | 10 studies | 28% ± 10% |
Insufficient scRNA-seq data for expression of GIPR at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| pancreas | 100% | 807.80 | 328 / 328 | 93% | 12.95 | 165 / 178 |
| lung | 98% | 715.94 | 567 / 578 | 65% | 2.42 | 746 / 1155 |
| breast | 99% | 1163.73 | 456 / 459 | 61% | 2.25 | 677 / 1118 |
| thymus | 83% | 325.92 | 541 / 653 | 49% | 1.01 | 296 / 605 |
| prostate | 89% | 958.86 | 218 / 245 | 38% | 0.92 | 192 / 502 |
| stomach | 77% | 1049.49 | 276 / 359 | 47% | 1.08 | 134 / 286 |
| bladder | 62% | 303.86 | 13 / 21 | 51% | 1.65 | 258 / 504 |
| intestine | 55% | 489.76 | 528 / 966 | 54% | 2.01 | 282 / 527 |
| kidney | 67% | 220.07 | 60 / 89 | 35% | 1.09 | 314 / 901 |
| skin | 77% | 353.33 | 1401 / 1809 | 22% | 0.48 | 106 / 472 |
| spleen | 99% | 518.12 | 239 / 241 | 0% | 0 | 0 / 0 |
| adipose | 97% | 1016.58 | 1167 / 1204 | 0% | 0 | 0 / 0 |
| brain | 57% | 204.92 | 1493 / 2642 | 40% | 0.87 | 282 / 705 |
| heart | 93% | 868.28 | 804 / 861 | 0% | 0 | 0 / 0 |
| esophagus | 36% | 109.79 | 513 / 1445 | 52% | 1.55 | 95 / 183 |
| lymph node | 0% | 0 | 0 / 0 | 72% | 1.70 | 21 / 29 |
| peripheral blood | 59% | 671.44 | 544 / 929 | 0% | 0 | 0 / 0 |
| uterus | 7% | 95.04 | 12 / 170 | 49% | 1.46 | 224 / 459 |
| tonsil | 0% | 0 | 0 / 0 | 42% | 0.85 | 19 / 45 |
| adrenal gland | 9% | 18.54 | 23 / 258 | 18% | 1.21 | 41 / 230 |
| liver | 7% | 10.78 | 16 / 226 | 19% | 1.15 | 77 / 406 |
| ovary | 1% | 0.71 | 1 / 180 | 13% | 0.27 | 56 / 430 |
| blood vessel | 8% | 28.24 | 110 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 5% | 0.07 | 4 / 80 |
| muscle | 1% | 1.07 | 7 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0007584 | Biological process | response to nutrient |
| GO_0050796 | Biological process | regulation of insulin secretion |
| GO_0006091 | Biological process | generation of precursor metabolites and energy |
| GO_0007188 | Biological process | adenylate cyclase-modulating G protein-coupled receptor signaling pathway |
| GO_0070542 | Biological process | response to fatty acid |
| GO_0009749 | Biological process | response to glucose |
| GO_0002029 | Biological process | desensitization of G protein-coupled receptor signaling pathway |
| GO_0048678 | Biological process | response to axon injury |
| GO_0032024 | Biological process | positive regulation of insulin secretion |
| GO_0007190 | Biological process | activation of adenylate cyclase activity |
| GO_0007204 | Biological process | positive regulation of cytosolic calcium ion concentration |
| GO_0043950 | Biological process | positive regulation of cAMP-mediated signaling |
| GO_0007189 | Biological process | adenylate cyclase-activating G protein-coupled receptor signaling pathway |
| GO_0031018 | Biological process | endocrine pancreas development |
| GO_0038192 | Biological process | gastric inhibitory peptide signaling pathway |
| GO_0051592 | Biological process | response to calcium ion |
| GO_0007166 | Biological process | cell surface receptor signaling pathway |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0004888 | Molecular function | transmembrane signaling receptor activity |
| GO_0017046 | Molecular function | peptide hormone binding |
| GO_0008528 | Molecular function | G protein-coupled peptide receptor activity |
| GO_0120022 | Molecular function | glucagon family peptide binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0016519 | Molecular function | gastric inhibitory peptide receptor activity |
| Gene name | GIPR |
| Protein name | Gastric inhibitory polypeptide receptor (GIP-R) (Glucose-dependent insulinotropic polypeptide receptor) Gastric inhibitory polypeptide receptor GIPR protein |
| Synonyms | |
| Description | FUNCTION: This is a receptor for GIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. |
| Accessions | ENST00000591322.1 K7EJZ3 A0A494C077 K7EPD9 ENST00000585889.1 ENST00000263281.7 [P48546-2] P48546 ENST00000304207.12 [P48546-3] ENST00000590918.6 [P48546-1] Q4VBP1 ENST00000652180.1 |
