Insufficient scRNA-seq data for expression of AGTR2 at single-cell level.
Insufficient scRNA-seq data for expression of AGTR2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
lung | 78% | 386.76 | 453 / 578 | 40% | 5.44 | 457 / 1155 |
uterus | 67% | 177.12 | 114 / 170 | 9% | 0.72 | 43 / 459 |
adrenal gland | 58% | 27.05 | 150 / 258 | 3% | 0.08 | 7 / 230 |
heart | 60% | 41.14 | 519 / 861 | 0% | 0 | 0 / 0 |
pancreas | 46% | 10.67 | 152 / 328 | 2% | 0.08 | 4 / 178 |
intestine | 40% | 14.35 | 390 / 966 | 1% | 0.02 | 3 / 527 |
stomach | 33% | 22.26 | 118 / 359 | 2% | 0.14 | 6 / 286 |
blood vessel | 25% | 9.16 | 329 / 1335 | 0% | 0 | 0 / 0 |
kidney | 20% | 4.00 | 18 / 89 | 2% | 0.04 | 15 / 901 |
ovary | 15% | 19.07 | 27 / 180 | 4% | 0.49 | 19 / 430 |
adipose | 19% | 6.39 | 223 / 1204 | 0% | 0 | 0 / 0 |
brain | 14% | 3.95 | 363 / 2642 | 0% | 0.02 | 1 / 705 |
esophagus | 8% | 1.49 | 113 / 1445 | 1% | 0.01 | 1 / 183 |
peripheral blood | 8% | 4.51 | 74 / 929 | 0% | 0 | 0 / 0 |
spleen | 7% | 2.03 | 17 / 241 | 0% | 0 | 0 / 0 |
bladder | 5% | 0.38 | 1 / 21 | 2% | 0.34 | 11 / 504 |
breast | 5% | 0.94 | 25 / 459 | 1% | 0.02 | 14 / 1118 |
thymus | 3% | 0.74 | 20 / 653 | 0% | 0 | 0 / 605 |
liver | 1% | 0.22 | 3 / 226 | 1% | 0.07 | 3 / 406 |
prostate | 2% | 0.25 | 5 / 245 | 0% | 0 | 0 / 502 |
muscle | 2% | 0.23 | 14 / 803 | 0% | 0 | 0 / 0 |
skin | 1% | 0.11 | 13 / 1809 | 1% | 0.02 | 4 / 472 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0035640 | Biological process | exploration behavior |
GO_2001238 | Biological process | positive regulation of extrinsic apoptotic signaling pathway |
GO_0001974 | Biological process | blood vessel remodeling |
GO_0006954 | Biological process | inflammatory response |
GO_0038060 | Biological process | nitric oxide-cGMP-mediated signaling |
GO_0007199 | Biological process | G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger |
GO_0008217 | Biological process | regulation of blood pressure |
GO_0010459 | Biological process | negative regulation of heart rate |
GO_0002035 | Biological process | brain renin-angiotensin system |
GO_0001991 | Biological process | regulation of systemic arterial blood pressure by circulatory renin-angiotensin |
GO_0002033 | Biological process | angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure |
GO_0072300 | Biological process | positive regulation of metanephric glomerulus development |
GO_0007166 | Biological process | cell surface receptor signaling pathway |
GO_0043537 | Biological process | negative regulation of blood vessel endothelial cell migration |
GO_0051402 | Biological process | neuron apoptotic process |
GO_0007186 | Biological process | G protein-coupled receptor signaling pathway |
GO_0045893 | Biological process | positive regulation of DNA-templated transcription |
GO_0038166 | Biological process | angiotensin-activated signaling pathway |
GO_0035566 | Biological process | regulation of metanephros size |
GO_0090190 | Biological process | positive regulation of branching involved in ureteric bud morphogenesis |
GO_0030308 | Biological process | negative regulation of cell growth |
GO_0007420 | Biological process | brain development |
GO_0032516 | Biological process | positive regulation of phosphoprotein phosphatase activity |
GO_0042311 | Biological process | vasodilation |
GO_0051387 | Biological process | negative regulation of neurotrophin TRK receptor signaling pathway |
GO_0005886 | Cellular component | plasma membrane |
GO_0048019 | Molecular function | receptor antagonist activity |
GO_0005515 | Molecular function | protein binding |
GO_0004945 | Molecular function | angiotensin type II receptor activity |
Gene name | AGTR2 |
Protein name | Type-2 angiotensin II receptor (Angiotensin II type-2 receptor) (AT2 receptor) |
Synonyms | |
Description | FUNCTION: Receptor for angiotensin II, a vasoconstricting peptide . Signals primarily via a non-canonical G-protein- and beta-arrestin independent pathways . Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation . . |
Accessions | P50052 ENST00000371906.5 ENST00000681852.1 |