FCGR3B | OmnibusX

Name	Number of supported studies	Average coverage
neutrophil	10 studies	55% ± 21%	Explore
non-classical monocyte	3 studies	32% ± 18%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of FCGR3B at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
lung	99%	2010.48	574 / 578	64%	4.37	735 / 1155
liver	81%	221.53	182 / 226	23%	2.16	95 / 406
spleen	100%	7338.19	241 / 241	0%	0	0 / 0
kidney	48%	128.09	43 / 89	50%	2.71	451 / 901
stomach	27%	127.85	97 / 359	64%	4.95	184 / 286
peripheral blood	81%	72863.87	755 / 929	0%	0	0 / 0
intestine	22%	59.66	210 / 966	58%	4.27	305 / 527
bladder	24%	441.71	5 / 21	50%	3.43	251 / 504
brain	25%	51.72	668 / 2642	39%	1.65	277 / 705
esophagus	19%	54.80	275 / 1445	45%	1.98	83 / 183
pancreas	9%	18.97	31 / 328	52%	3.38	93 / 178
adipose	61%	373.82	739 / 1204	0%	0	0 / 0
uterus	25%	76.42	42 / 170	36%	2.03	164 / 459
skin	37%	137.76	675 / 1809	22%	0.78	103 / 472
breast	30%	67.43	138 / 459	23%	2.12	260 / 1118
heart	53%	158.58	458 / 861	0%	0	0 / 0
prostate	30%	57.40	73 / 245	16%	0.35	78 / 502
thymus	35%	79.93	229 / 653	7%	0.22	45 / 605
tonsil	0%	0	0 / 0	40%	1.45	18 / 45
adrenal gland	16%	19.65	40 / 258	23%	1.23	52 / 230
ovary	9%	21.83	17 / 180	19%	0.66	81 / 430
blood vessel	25%	86.76	335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	17%	1.98	5 / 29
muscle	13%	20.60	106 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0006955	Biological process	immune response
GO_0001788	Biological process	antibody-dependent cellular cytotoxicity
GO_0038094	Biological process	Fc-gamma receptor signaling pathway
GO_0007166	Biological process	cell surface receptor signaling pathway
GO_0030667	Cellular component	secretory granule membrane
GO_0070062	Cellular component	extracellular exosome
GO_0009897	Cellular component	external side of plasma membrane
GO_0005576	Cellular component	extracellular region
GO_0005886	Cellular component	plasma membrane
GO_0019864	Molecular function	IgG binding
GO_0034235	Molecular function	GPI anchor binding
GO_0019770	Molecular function	IgG receptor activity

Gene name	FCGR3B
Protein name	Low affinity immunoglobulin gamma Fc region receptor III-B (Fc-gamma RIII-beta) (CD16-I) (Fc-gamma RIII) (Fc-gamma RIIIb) (FcRIII) (FcRIIIb) (FcR-10) (IgG Fc receptor III-1) (CD antigen CD16b) Low affinity immunoglobulin gamma Fc region receptor III-A Fc gamma receptor IIIb Fc gamma receptor III-B
Synonyms	IGFR3 FCGR3 FCG3 CD16B
Description	FUNCTION: Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.
Accessions	ENST00000367964.6 ENST00000534776.1 A0A3B3ISU3 O75015 A0A5A4UD02 H0Y4U3 ENST00000421702.4 E9PNY5 ENST00000650385.1

FCGR3B report