Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| retinal rod cell | 9 studies | 86% ± 23% | |
| retinal cone cell | 6 studies | 36% ± 16% | |
| amacrine cell | 5 studies | 37% ± 8% | |
| retinal bipolar neuron | 3 studies | 49% ± 8% | |
| retinal ganglion cell | 3 studies | 48% ± 29% | |
| microglial cell | 3 studies | 55% ± 8% | |
| Mueller cell | 3 studies | 41% ± 18% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| eye | 7 studies | 59% ± 21% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 39% | 55.24 | 1034 / 2642 | 0% | 0 | 0 / 705 |
| uterus | 29% | 13.52 | 49 / 170 | 1% | 0.03 | 4 / 459 |
| intestine | 25% | 3.70 | 242 / 966 | 0% | 0.00 | 1 / 527 |
| peripheral blood | 18% | 2.05 | 164 / 929 | 0% | 0 | 0 / 0 |
| breast | 6% | 0.85 | 27 / 459 | 1% | 0.01 | 7 / 1118 |
| eye | 0% | 0 | 0 / 0 | 6% | 3.99 | 5 / 80 |
| muscle | 5% | 0.75 | 44 / 803 | 0% | 0 | 0 / 0 |
| spleen | 5% | 0.78 | 11 / 241 | 0% | 0 | 0 / 0 |
| prostate | 3% | 0.59 | 8 / 245 | 0% | 0 | 0 / 502 |
| lung | 3% | 0.27 | 16 / 578 | 0% | 0.00 | 2 / 1155 |
| esophagus | 1% | 0.15 | 15 / 1445 | 1% | 0.02 | 2 / 183 |
| adrenal gland | 0% | 0 | 0 / 258 | 2% | 0.02 | 4 / 230 |
| thymus | 2% | 0.20 | 10 / 653 | 0% | 0 | 0 / 605 |
| ovary | 1% | 0.11 | 2 / 180 | 0% | 0.01 | 1 / 430 |
| adipose | 1% | 0.12 | 12 / 1204 | 0% | 0 | 0 / 0 |
| stomach | 1% | 0.05 | 2 / 359 | 0% | 0.00 | 1 / 286 |
| liver | 1% | 0.10 | 2 / 226 | 0% | 0 | 0 / 406 |
| skin | 1% | 4.13 | 16 / 1809 | 0% | 0 | 0 / 472 |
| blood vessel | 1% | 0.08 | 11 / 1335 | 0% | 0 | 0 / 0 |
| heart | 1% | 0.08 | 5 / 861 | 0% | 0 | 0 / 0 |
| pancreas | 0% | 0.02 | 1 / 328 | 0% | 0 | 0 / 178 |
| kidney | 0% | 0 | 0 / 89 | 0% | 0.01 | 1 / 901 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bladder | 0% | 0 | 0 / 21 | 0% | 0 | 0 / 504 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0016056 | Biological process | G protein-coupled opsin signaling pathway |
| GO_0007166 | Biological process | cell surface receptor signaling pathway |
| GO_0002031 | Biological process | G protein-coupled receptor internalization |
| GO_0001917 | Cellular component | photoreceptor inner segment |
| GO_0005829 | Cellular component | cytosol |
| GO_0001750 | Cellular component | photoreceptor outer segment |
| GO_0016020 | Cellular component | membrane |
| GO_0004864 | Molecular function | protein phosphatase inhibitor activity |
| GO_0051219 | Molecular function | phosphoprotein binding |
| GO_0002046 | Molecular function | opsin binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0001664 | Molecular function | G protein-coupled receptor binding |
| Gene name | SAG |
| Protein name | S-arrestin (48 kDa protein) (Retinal S-antigen) (Rod photoreceptor arrestin) 48 kDa protein S-arrestin (48 kDa protein) (Retinal S-antigen) (S-AG) (Rod photoreceptor arrestin) S-antigen visual arrestin (S-arrestin) |
| Synonyms | |
| Description | FUNCTION: Binds to photoactivated, phosphorylated RHO and terminates RHO signaling via G-proteins by competing with G-proteins for the same binding site on RHO (By similarity). May play a role in preventing light-dependent degeneration of retinal photoreceptor cells . . |
| Accessions | E7ESX4 ENST00000631149.3 ENST00000628376 F8WCN5 ENST00000453143.5 ENST00000625330 ENST00000447536.5 P10523 ENST00000630167 ENST00000415974.1 ENST00000409110.6 C9JSX4 |
