FCGR2A report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0050766Biological processpositive regulation of phagocytosis
GO_0001788Biological processantibody-dependent cellular cytotoxicity
GO_0032760Biological processpositive regulation of tumor necrosis factor production
GO_0038094Biological processFc-gamma receptor signaling pathway
GO_0007166Biological processcell surface receptor signaling pathway
GO_0030667Cellular componentsecretory granule membrane
GO_0009897Cellular componentexternal side of plasma membrane
GO_0005886Cellular componentplasma membrane
GO_0019864Molecular functionIgG binding
GO_0019770Molecular functionIgG receptor activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameFCGR2A
Protein nameFc gamma receptor IIa
Low affinity immunoglobulin gamma Fc region receptor II-a (IgG Fc receptor II-a) (CDw32) (Fc-gamma RII-a) (Fc-gamma-RIIa) (FcRII-a) (CD antigen CD32)
Fc gamma receptor RIIa3 splice variant
SynonymsIGFR2
FCGR2A1
FCG2
CD32
DescriptionFUNCTION: Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens. .

AccessionsENST00000536731.5
V9GY83
F5GX41
ENST00000367972.8 [P12318-2]
ENST00000483665.6
A0A8V8TPS4
A0A8V8TN30
ENST00000699279.1
V9GY55
A0A346JF56
ENST00000699278.1
ENST00000459885.1
ENST00000467525.5
ENST00000271450.12 [P12318-1]
F5GXY9
ENST00000699277.1
P12318
A0A8V8TN00