Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 17 studies | 30% ± 11% | |
astrocyte | 14 studies | 55% ± 21% | |
oligodendrocyte | 11 studies | 30% ± 12% | |
CD4-positive, alpha-beta T cell | 9 studies | 22% ± 5% | |
microglial cell | 9 studies | 25% ± 9% | |
T cell | 7 studies | 22% ± 8% | |
macrophage | 6 studies | 21% ± 5% | |
naive thymus-derived CD4-positive, alpha-beta T cell | 5 studies | 28% ± 13% | |
regulatory T cell | 5 studies | 18% ± 2% | |
endothelial cell of lymphatic vessel | 5 studies | 24% ± 4% | |
natural killer cell | 4 studies | 22% ± 4% | |
effector memory CD8-positive, alpha-beta T cell | 4 studies | 21% ± 2% | |
retinal pigment epithelial cell | 4 studies | 28% ± 16% | |
CD8-positive, alpha-beta T cell | 4 studies | 20% ± 4% | |
CD4-positive, alpha-beta memory T cell | 3 studies | 27% ± 13% | |
endothelial cell of vascular tree | 3 studies | 21% ± 5% | |
ependymal cell | 3 studies | 56% ± 10% | |
capillary endothelial cell | 3 studies | 21% ± 5% | |
lymphocyte | 3 studies | 31% ± 10% | |
kidney distal convoluted tubule epithelial cell | 3 studies | 29% ± 6% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 6 studies | 30% ± 10% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 12083.35 | 2636 / 2642 | 100% | 126.04 | 703 / 705 |
prostate | 100% | 4384.59 | 244 / 245 | 100% | 41.62 | 501 / 502 |
breast | 100% | 5306.19 | 458 / 459 | 97% | 32.99 | 1079 / 1118 |
lung | 99% | 5879.06 | 575 / 578 | 92% | 29.02 | 1058 / 1155 |
esophagus | 99% | 9359.69 | 1425 / 1445 | 91% | 26.48 | 167 / 183 |
uterus | 100% | 12292.99 | 170 / 170 | 89% | 26.44 | 410 / 459 |
thymus | 90% | 2330.86 | 590 / 653 | 98% | 30.02 | 595 / 605 |
ovary | 93% | 2363.43 | 168 / 180 | 92% | 25.99 | 396 / 430 |
bladder | 100% | 10515.57 | 21 / 21 | 79% | 15.44 | 399 / 504 |
kidney | 98% | 3402.25 | 87 / 89 | 79% | 19.13 | 711 / 901 |
skin | 73% | 3509.37 | 1326 / 1809 | 100% | 155.25 | 471 / 472 |
intestine | 96% | 9083.83 | 927 / 966 | 72% | 12.25 | 382 / 527 |
stomach | 78% | 4980.89 | 279 / 359 | 80% | 18.75 | 228 / 286 |
pancreas | 9% | 151.02 | 29 / 328 | 92% | 18.71 | 163 / 178 |
eye | 0% | 0 | 0 / 0 | 100% | 252.44 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 55.59 | 29 / 29 |
spleen | 100% | 6099.24 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 17.44 | 1 / 1 |
adipose | 100% | 5608.37 | 1203 / 1204 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 98% | 30.86 | 44 / 45 |
peripheral blood | 88% | 3482.89 | 819 / 929 | 0% | 0 | 0 / 0 |
blood vessel | 78% | 1911.38 | 1046 / 1335 | 0% | 0 | 0 / 0 |
heart | 66% | 1522.52 | 569 / 861 | 0% | 0 | 0 / 0 |
adrenal gland | 34% | 615.77 | 88 / 258 | 31% | 6.22 | 72 / 230 |
muscle | 20% | 346.54 | 162 / 803 | 0% | 0 | 0 / 0 |
liver | 1% | 18.45 | 2 / 226 | 8% | 1.48 | 31 / 406 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0045638 | Biological process | negative regulation of myeloid cell differentiation |
GO_0002262 | Biological process | myeloid cell homeostasis |
GO_0000165 | Biological process | MAPK cascade |
GO_0032958 | Biological process | inositol phosphate biosynthetic process |
GO_0007165 | Biological process | signal transduction |
GO_0033030 | Biological process | negative regulation of neutrophil apoptotic process |
GO_0046854 | Biological process | phosphatidylinositol phosphate biosynthetic process |
GO_0001932 | Biological process | regulation of protein phosphorylation |
GO_0071277 | Biological process | cellular response to calcium ion |
GO_0035726 | Biological process | common myeloid progenitor cell proliferation |
GO_0046579 | Biological process | positive regulation of Ras protein signal transduction |
GO_0045059 | Biological process | positive thymic T cell selection |
GO_0046638 | Biological process | positive regulation of alpha-beta T cell differentiation |
GO_0032957 | Biological process | inositol trisphosphate metabolic process |
GO_0007166 | Biological process | cell surface receptor signaling pathway |
GO_0005856 | Cellular component | cytoskeleton |
GO_0016020 | Cellular component | membrane |
GO_0005783 | Cellular component | endoplasmic reticulum |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0051765 | Molecular function | inositol tetrakisphosphate kinase activity |
GO_0008440 | Molecular function | inositol-1,4,5-trisphosphate 3-kinase activity |
GO_0005524 | Molecular function | ATP binding |
GO_0005516 | Molecular function | calmodulin binding |
GO_0005515 | Molecular function | protein binding |
Gene name | ITPKB |
Protein name | Inositol-trisphosphate 3-kinase B (EC 2.7.1.127) (Inositol 1,4,5-trisphosphate 3-kinase B) (IP3 3-kinase B) (IP3K B) (InsP 3-kinase B) |
Synonyms | |
Description | FUNCTION: Catalyzes the phosphorylation of 1D-myo-inositol 1,4,5-trisphosphate (InsP3) into 1D-myo-inositol 1,3,4,5-tetrakisphosphate and participates to the regulation of calcium homeostasis. . |
Accessions | ENST00000429204.6 [P27987-1] ENST00000272117.8 [P27987-1] ENST00000366784.1 [P27987-2] P27987 |