Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 31 studies | 41% ± 20% | |
pericyte | 12 studies | 32% ± 15% | |
fibroblast | 12 studies | 32% ± 19% | |
glutamatergic neuron | 11 studies | 67% ± 20% | |
GABAergic neuron | 10 studies | 53% ± 23% | |
capillary endothelial cell | 9 studies | 49% ± 24% | |
adipocyte | 9 studies | 29% ± 10% | |
vein endothelial cell | 9 studies | 36% ± 22% | |
cardiac muscle cell | 6 studies | 51% ± 20% | |
endothelial cell of vascular tree | 5 studies | 25% ± 11% | |
smooth muscle cell | 5 studies | 27% ± 4% | |
hepatocyte | 4 studies | 42% ± 24% | |
neuron | 4 studies | 32% ± 14% | |
retinal bipolar neuron | 4 studies | 56% ± 31% | |
epithelial cell | 4 studies | 29% ± 8% | |
Mueller cell | 4 studies | 56% ± 29% | |
interneuron | 4 studies | 51% ± 19% | |
endothelial cell of sinusoid | 3 studies | 47% ± 16% | |
hepatic stellate cell | 3 studies | 49% ± 9% | |
glomerular endothelial cell | 3 studies | 29% ± 3% | |
ON-bipolar cell | 3 studies | 77% ± 30% | |
retina horizontal cell | 3 studies | 47% ± 21% | |
rod bipolar cell | 3 studies | 78% ± 28% | |
connective tissue cell | 3 studies | 26% ± 8% | |
mesothelial cell | 3 studies | 28% ± 6% | |
kidney distal convoluted tubule epithelial cell | 3 studies | 33% ± 11% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
kidney | 100% | 3155.47 | 89 / 89 | 96% | 14.02 | 867 / 901 |
thymus | 100% | 8354.59 | 653 / 653 | 92% | 13.25 | 559 / 605 |
prostate | 100% | 5282.74 | 244 / 245 | 91% | 8.77 | 458 / 502 |
esophagus | 100% | 4493.21 | 1445 / 1445 | 90% | 9.08 | 165 / 183 |
ovary | 100% | 6273.47 | 180 / 180 | 90% | 11.64 | 386 / 430 |
lung | 100% | 13428.38 | 578 / 578 | 84% | 6.38 | 966 / 1155 |
breast | 100% | 4029.37 | 459 / 459 | 82% | 6.15 | 915 / 1118 |
liver | 100% | 2669.07 | 226 / 226 | 79% | 5.03 | 320 / 406 |
uterus | 100% | 2390.56 | 170 / 170 | 77% | 8.39 | 355 / 459 |
adrenal gland | 100% | 4075.68 | 258 / 258 | 68% | 4.97 | 157 / 230 |
pancreas | 79% | 956.91 | 258 / 328 | 86% | 5.49 | 153 / 178 |
stomach | 100% | 2602.84 | 359 / 359 | 57% | 3.44 | 164 / 286 |
bladder | 100% | 2846.95 | 21 / 21 | 50% | 3.45 | 250 / 504 |
brain | 72% | 1362.71 | 1904 / 2642 | 68% | 4.52 | 480 / 705 |
skin | 99% | 2559.00 | 1787 / 1809 | 40% | 3.62 | 188 / 472 |
intestine | 98% | 2929.99 | 947 / 966 | 38% | 1.99 | 202 / 527 |
adipose | 100% | 4158.31 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 3758.47 | 1335 / 1335 | 0% | 0 | 0 / 0 |
spleen | 100% | 3619.58 | 241 / 241 | 0% | 0 | 0 / 0 |
heart | 99% | 3353.72 | 851 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 84% | 7.89 | 38 / 45 |
muscle | 31% | 297.54 | 250 / 803 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 10% | 0.23 | 3 / 29 |
eye | 0% | 0 | 0 / 0 | 1% | 0.06 | 1 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0007186 | Biological process | G protein-coupled receptor signaling pathway |
GO_0007189 | Biological process | adenylate cyclase-activating G protein-coupled receptor signaling pathway |
GO_0007166 | Biological process | cell surface receptor signaling pathway |
GO_0005886 | Cellular component | plasma membrane |
GO_0016020 | Cellular component | membrane |
GO_0016524 | Molecular function | latrotoxin receptor activity |
GO_0004930 | Molecular function | G protein-coupled receptor activity |
GO_0030246 | Molecular function | carbohydrate binding |
Gene name | ADGRL2 |
Protein name | Adhesion G protein-coupled receptor L2 (Latrophilin 2, isoform CRA_f) Adhesion G protein-coupled receptor L2 (Latrophilin 2, isoform CRA_b) Adhesion G protein-coupled receptor L2 Adhesion G protein-coupled receptor L2 (Latrophilin 2, isoform CRA_k) Adhesion G protein-coupled receptor L2 (Calcium-independent alpha-latrotoxin receptor 2) (CIRL-2) (Latrophilin homolog 1) (Latrophilin-2) (Lectomedin-1) |
Synonyms | LEC1 LPHH1 hCG_14669 LPHN2 KIAA0786 |
Description | FUNCTION: Calcium-independent receptor of low affinity for alpha-latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis. . |
Accessions | A0A6I8PIV6 B1ALU1 ENST00000370728.5 [O95490-1] B1ALU3 ENST00000370715.5 [O95490-4] A0A6I8PU30 O95490 ENST00000674407.1 ENST00000449420.5 A0A6I8PUE4 H0Y3V3 ENST00000674208.1 A0A8I5KUX3 ENST00000674373.1 ENST00000686636.1 ENST00000674168.1 A0A6I8PTT2 ENST00000674307.1 ENST00000370730.5 [O95490-5] ENST00000674492.1 A0A6I8PRM6 ENST00000674393.1 [O95490-2] A0A6I8PRJ0 ENST00000674419.1 [O95490-5] ENST00000402328.2 ENST00000370721.5 ENST00000370725.5 [O95490-6] ENST00000370717.6 [O95490-1] ENST00000674489.1 ENST00000370727.5 ENST00000627151.2 ENST00000370713.5 [O95490-3] A0A6I8PLG0 ENST00000370723.5 [O95490-7] ENST00000359929.7 [O95490-2] ENST00000674209.1 H0Y5C0 ENST00000319517.10 [O95490-2] A0A6I8PRQ0 ENST00000674442.1 |