ADGRG5 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ADGRG5 at tissue level.

III. Associated gene sets

GO_0007186Biological processG protein-coupled receptor signaling pathway
GO_0007189Biological processadenylate cyclase-activating G protein-coupled receptor signaling pathway
GO_0007166Biological processcell surface receptor signaling pathway
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0004930Molecular functionG protein-coupled receptor activity

IV. Literature review

[source]
Gene nameADGRG5
Protein nameAdhesion G protein-coupled receptor G5
Adhesion G-protein coupled receptor G5 (G-protein coupled receptor 114) (G-protein coupled receptor PGR27)
SynonymsGPR114
PGR27
UNQ2524/PRO6017
DescriptionFUNCTION: Adhesion G protein-coupled receptor (GPCR). Transduces intracellular signals through coupling to guanine nucleotide-binding protein G(s) subunit alpha and activation of adenylate cyclase pathway. Isoform 1, but not isoform 2, is constitutively active, as evidenced by elevated basal cAMP levels, and responds to mechanical activation (shaking). .

AccessionsENST00000349457.8
Q8IZF4
ENST00000615867.4
ENST00000340339.4
A0A087WZA0