Insufficient scRNA-seq data for expression of GLP1R at single-cell level.
Insufficient scRNA-seq data for expression of GLP1R at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
pancreas | 100% | 552.00 | 328 / 328 | 66% | 3.73 | 117 / 178 |
thymus | 75% | 26.41 | 491 / 653 | 38% | 3.00 | 228 / 605 |
stomach | 87% | 56.37 | 311 / 359 | 8% | 0.27 | 22 / 286 |
heart | 91% | 205.00 | 787 / 861 | 0% | 0 | 0 / 0 |
lung | 74% | 31.73 | 425 / 578 | 9% | 0.42 | 109 / 1155 |
brain | 41% | 31.06 | 1085 / 2642 | 37% | 2.49 | 260 / 705 |
breast | 48% | 18.22 | 220 / 459 | 20% | 0.95 | 220 / 1118 |
skin | 41% | 15.58 | 736 / 1809 | 7% | 0.38 | 34 / 472 |
adrenal gland | 9% | 2.16 | 24 / 258 | 36% | 11.48 | 82 / 230 |
prostate | 31% | 8.59 | 76 / 245 | 13% | 1.17 | 65 / 502 |
kidney | 22% | 5.13 | 20 / 89 | 16% | 0.62 | 148 / 901 |
blood vessel | 26% | 13.13 | 351 / 1335 | 0% | 0 | 0 / 0 |
adipose | 24% | 6.10 | 286 / 1204 | 0% | 0 | 0 / 0 |
liver | 1% | 0.14 | 2 / 226 | 14% | 0.84 | 55 / 406 |
intestine | 8% | 1.43 | 74 / 966 | 6% | 0.30 | 31 / 527 |
esophagus | 4% | 1.23 | 59 / 1445 | 9% | 0.31 | 16 / 183 |
uterus | 5% | 1.02 | 8 / 170 | 8% | 0.30 | 36 / 459 |
ovary | 1% | 0.07 | 1 / 180 | 12% | 0.34 | 51 / 430 |
peripheral blood | 9% | 2.28 | 84 / 929 | 0% | 0 | 0 / 0 |
bladder | 0% | 0 | 0 / 21 | 8% | 0.29 | 38 / 504 |
lymph node | 0% | 0 | 0 / 0 | 7% | 0.37 | 2 / 29 |
eye | 0% | 0 | 0 / 0 | 6% | 0.09 | 5 / 80 |
spleen | 6% | 1.02 | 15 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 2% | 0.09 | 1 / 45 |
muscle | 1% | 0.20 | 7 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0045777 | Biological process | positive regulation of blood pressure |
GO_0007611 | Biological process | learning or memory |
GO_1990911 | Biological process | response to psychosocial stress |
GO_0019933 | Biological process | cAMP-mediated signaling |
GO_0031204 | Biological process | post-translational protein targeting to membrane, translocation |
GO_0007190 | Biological process | activation of adenylate cyclase activity |
GO_0045776 | Biological process | negative regulation of blood pressure |
GO_0007204 | Biological process | positive regulation of cytosolic calcium ion concentration |
GO_0046879 | Biological process | hormone secretion |
GO_0071377 | Biological process | cellular response to glucagon stimulus |
GO_0007189 | Biological process | adenylate cyclase-activating G protein-coupled receptor signaling pathway |
GO_0008016 | Biological process | regulation of heart contraction |
GO_0007166 | Biological process | cell surface receptor signaling pathway |
GO_0005886 | Cellular component | plasma membrane |
GO_0016020 | Cellular component | membrane |
GO_0004967 | Molecular function | glucagon receptor activity |
GO_0004888 | Molecular function | transmembrane signaling receptor activity |
GO_0017046 | Molecular function | peptide hormone binding |
GO_0044508 | Molecular function | glucagon-like peptide 1 receptor activity |
GO_0005515 | Molecular function | protein binding |
Gene name | GLP1R |
Protein name | Glucagon-like peptide-1 receptor Glucagon-like peptide 1 receptor (GLP-1 receptor) (GLP-1-R) (GLP-1R) |
Synonyms | |
Description | FUNCTION: G-protein coupled receptor for glucagon-like peptide 1 (GLP-1) . Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels . Plays a role in regulating insulin secretion in response to GLP-1 (By similarity). . |
Accessions | ENST00000373256.5 A0A142FHB8 P43220 |