ATP1A4 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of ATP1A4 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ATP1A4 at tissue level.

III. Associated gene sets

GO_0006813Biological processpotassium ion transport
GO_0007283Biological processspermatogenesis
GO_0042391Biological processregulation of membrane potential
GO_0036376Biological processsodium ion export across plasma membrane
GO_0150104Biological processtransport across blood-brain barrier
GO_0006811Biological processmonoatomic ion transport
GO_0006883Biological processintracellular sodium ion homeostasis
GO_0051649Biological processestablishment of localization in cell
GO_0071805Biological processpotassium ion transmembrane transport
GO_0030641Biological processregulation of cellular pH
GO_0009566Biological processfertilization
GO_1990573Biological processpotassium ion import across plasma membrane
GO_0030317Biological processflagellated sperm motility
GO_0006814Biological processsodium ion transport
GO_0010248Biological processestablishment or maintenance of transmembrane electrochemical gradient
GO_0030007Biological processintracellular potassium ion homeostasis
GO_0035725Biological processsodium ion transmembrane transport
GO_1902600Biological processproton transmembrane transport
GO_0007166Biological processcell surface receptor signaling pathway
GO_0005890Cellular componentsodium:potassium-exchanging ATPase complex
GO_0005886Cellular componentplasma membrane
GO_0045121Cellular componentmembrane raft
GO_0042995Cellular componentcell projection
GO_0097225Cellular componentsperm midpiece
GO_0097733Cellular componentphotoreceptor cell cilium
GO_0120200Cellular componentrod photoreceptor outer segment
GO_0019829Molecular functionATPase-coupled monoatomic cation transmembrane transporter activity
GO_0019900Molecular functionkinase binding
GO_0005391Molecular functionP-type sodium:potassium-exchanging transporter activity
GO_0046872Molecular functionmetal ion binding
GO_0005524Molecular functionATP binding
GO_0005515Molecular functionprotein binding
GO_0016887Molecular functionATP hydrolysis activity

IV. Literature review

[source]
Gene nameATP1A4
Protein nameSodium/potassium-transporting ATPase subunit alpha-4 (Na(+)/K(+) ATPase alpha-4 subunit) (EC 7.2.2.13) (Sodium pump subunit alpha-4)
ATPase Na+/K+ transporting subunit alpha 4
SynonymsATP1AL2
DescriptionFUNCTION: This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients. Plays a role in sperm motility.

AccessionsENST00000477338.5
ENST00000469023.5
Q13733
ENST00000368081.9 [Q13733-1]
A0A669K9X0
E9PRA5
ENST00000470705.1 [Q13733-2]