Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 30 studies | 32% ± 16% | |
endothelial cell of lymphatic vessel | 19 studies | 43% ± 20% | |
oligodendrocyte | 15 studies | 52% ± 17% | |
astrocyte | 15 studies | 33% ± 12% | |
oligodendrocyte precursor cell | 13 studies | 40% ± 16% | |
capillary endothelial cell | 10 studies | 29% ± 11% | |
vein endothelial cell | 9 studies | 32% ± 20% | |
GABAergic neuron | 7 studies | 32% ± 16% | |
epithelial cell | 6 studies | 24% ± 7% | |
interneuron | 6 studies | 30% ± 13% | |
retina horizontal cell | 6 studies | 48% ± 15% | |
neuron | 5 studies | 34% ± 15% | |
amacrine cell | 5 studies | 25% ± 7% | |
endothelial cell of vascular tree | 5 studies | 25% ± 6% | |
glutamatergic neuron | 5 studies | 35% ± 16% | |
endothelial cell of sinusoid | 4 studies | 37% ± 20% | |
glomerular endothelial cell | 3 studies | 33% ± 5% | |
granule cell | 3 studies | 45% ± 16% | |
placental villous trophoblast | 3 studies | 36% ± 20% | |
GABAergic amacrine cell | 3 studies | 39% ± 5% | |
enteroendocrine cell | 3 studies | 17% ± 1% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 3891.05 | 2640 / 2642 | 99% | 46.88 | 701 / 705 |
kidney | 100% | 2119.35 | 89 / 89 | 88% | 29.08 | 797 / 901 |
adrenal gland | 100% | 16235.85 | 258 / 258 | 87% | 19.93 | 199 / 230 |
prostate | 99% | 1562.02 | 243 / 245 | 65% | 7.44 | 324 / 502 |
skin | 71% | 1232.33 | 1281 / 1809 | 87% | 39.38 | 409 / 472 |
bladder | 100% | 1370.52 | 21 / 21 | 57% | 9.81 | 285 / 504 |
pancreas | 99% | 1672.58 | 326 / 328 | 56% | 6.22 | 99 / 178 |
intestine | 100% | 4259.46 | 966 / 966 | 48% | 5.58 | 251 / 527 |
esophagus | 97% | 1510.92 | 1407 / 1445 | 48% | 8.93 | 87 / 183 |
breast | 100% | 3621.68 | 459 / 459 | 42% | 5.60 | 475 / 1118 |
uterus | 100% | 1935.56 | 170 / 170 | 37% | 7.81 | 169 / 459 |
stomach | 82% | 1648.95 | 295 / 359 | 55% | 8.31 | 156 / 286 |
lung | 100% | 4757.68 | 577 / 578 | 35% | 4.95 | 410 / 1155 |
thymus | 100% | 2544.04 | 652 / 653 | 27% | 2.30 | 162 / 605 |
ovary | 100% | 4248.98 | 180 / 180 | 23% | 2.88 | 98 / 430 |
adipose | 100% | 3005.87 | 1204 / 1204 | 0% | 0 | 0 / 0 |
spleen | 100% | 3104.61 | 241 / 241 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 99% | 37.90 | 79 / 80 |
heart | 89% | 854.90 | 764 / 861 | 0% | 0 | 0 / 0 |
liver | 59% | 516.27 | 133 / 226 | 26% | 7.45 | 106 / 406 |
tonsil | 0% | 0 | 0 / 0 | 58% | 9.60 | 26 / 45 |
blood vessel | 57% | 653.07 | 756 / 1335 | 0% | 0 | 0 / 0 |
muscle | 49% | 359.20 | 397 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 17% | 425.84 | 154 / 929 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 7% | 0.63 | 2 / 29 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0001755 | Biological process | neural crest cell migration |
GO_0009887 | Biological process | animal organ morphogenesis |
GO_2001224 | Biological process | positive regulation of neuron migration |
GO_0070373 | Biological process | negative regulation of ERK1 and ERK2 cascade |
GO_1903671 | Biological process | negative regulation of sprouting angiogenesis |
GO_0007010 | Biological process | cytoskeleton organization |
GO_0050919 | Biological process | negative chemotaxis |
GO_0016525 | Biological process | negative regulation of angiogenesis |
GO_0106089 | Biological process | negative regulation of cell adhesion involved in sprouting angiogenesis |
GO_1900747 | Biological process | negative regulation of vascular endothelial growth factor signaling pathway |
GO_0006915 | Biological process | apoptotic process |
GO_0071526 | Biological process | semaphorin-plexin signaling pathway |
GO_0035924 | Biological process | cellular response to vascular endothelial growth factor stimulus |
GO_0007399 | Biological process | nervous system development |
GO_0007411 | Biological process | axon guidance |
GO_0007166 | Biological process | cell surface receptor signaling pathway |
GO_0005886 | Cellular component | plasma membrane |
GO_0016020 | Cellular component | membrane |
GO_0030424 | Cellular component | axon |
GO_0030215 | Molecular function | semaphorin receptor binding |
GO_0045499 | Molecular function | chemorepellent activity |
GO_0005515 | Molecular function | protein binding |
Gene name | SEMA6A |
Protein name | Semaphorin 6A Sema domain, transmembrane domain (TM), and cytoplasmic domain, (Semaphorin) 6A, isoform CRA_d (Semaphorin-6A) Semaphorin-6A (Semaphorin VIA) (Sema VIA) (Semaphorin-6A-1) (SEMA6A-1) Semaphorin 6A (cDNA FLJ39018 fis, clone NT2RP7002594, highly similar to Semaphorin-6A) |
Synonyms | hCG_2028216 SEMAQ KIAA1368 |
Description | FUNCTION: Cell surface receptor for PLXNA2 that plays an important role in cell-cell signaling. Required for normal granule cell migration in the developing cerebellum. Promotes reorganization of the actin cytoskeleton and plays an important role in axon guidance in the developing central nervous system. Can act as repulsive axon guidance cue. Has repulsive action towards migrating granular neurons. May play a role in channeling sympathetic axons into the sympathetic chains and controlling the temporal sequence of sympathetic target innervation. .; FUNCTION: (Microbial infection) Acts as a receptor for P.sordellii toxin TcsL in the in the vascular endothelium. . |
Accessions | ENST00000515129.5 A0A0A0MQU6 ENST00000510263.5 [Q9H2E6-1] ENST00000343348.11 [Q9H2E6-1] ENST00000257414.12 [Q9H2E6-2] ENST00000503865.1 H0Y8V9 ENST00000513137.5 D6RAG9 ENST00000515009.5 ENST00000509665.1 D6RCR0 ENST00000257414 B3KU01 E9PDV9 Q9H2E6 |