CRHR2 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of CRHR2 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
thymus	97%	142.15	633 / 653	45%	1.14	275 / 605
ovary	91%	67.44	163 / 180	10%	0.23	44 / 430
brain	81%	151.16	2129 / 2642	16%	0.36	112 / 705
pancreas	90%	164.14	294 / 328	4%	0.14	8 / 178
bladder	86%	73.43	18 / 21	8%	0.18	39 / 504
breast	89%	119.19	410 / 459	2%	0.04	24 / 1118
heart	89%	133.03	766 / 861	0%	0	0 / 0
uterus	84%	64.61	142 / 170	3%	0.08	16 / 459
esophagus	80%	52.62	1152 / 1445	7%	0.11	13 / 183
muscle	81%	68.00	651 / 803	0%	0	0 / 0
adipose	80%	95.60	969 / 1204	0%	0	0 / 0
intestine	74%	44.08	715 / 966	3%	0.04	15 / 527
prostate	65%	41.72	159 / 245	1%	0.08	5 / 502
stomach	52%	24.54	188 / 359	5%	0.07	13 / 286
skin	53%	28.88	953 / 1809	0%	0.01	2 / 472
lung	35%	15.82	203 / 578	16%	0.65	182 / 1155
blood vessel	46%	27.92	610 / 1335	0%	0	0 / 0
kidney	15%	17.45	13 / 89	16%	0.38	142 / 901
adrenal gland	12%	4.72	30 / 258	8%	0.28	19 / 230
liver	4%	1.00	8 / 226	4%	0.09	17 / 406
spleen	6%	1.81	15 / 241	0%	0	0 / 0
peripheral blood	3%	1.20	27 / 929	0%	0	0 / 0
tonsil	0%	0	0 / 0	2%	0.16	1 / 45
eye	0%	0	0 / 0	1%	0.03	1 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0071376	Biological process	cellular response to corticotropin-releasing hormone stimulus
GO_0007188	Biological process	adenylate cyclase-modulating G protein-coupled receptor signaling pathway
GO_0060291	Biological process	long-term synaptic potentiation
GO_0007166	Biological process	cell surface receptor signaling pathway
GO_0043679	Cellular component	axon terminus
GO_0005886	Cellular component	plasma membrane
GO_0030425	Cellular component	dendrite
GO_0008528	Molecular function	G protein-coupled peptide receptor activity
GO_0017046	Molecular function	peptide hormone binding
GO_0043404	Molecular function	corticotropin-releasing hormone receptor activity
GO_0005515	Molecular function	protein binding
GO_0015056	Molecular function	corticotrophin-releasing factor receptor activity

Gene name	CRHR2
Protein name	Corticotropin-releasing factor receptor 2 (CRF-R-2) (CRF-R2) (CRFR-2) (Corticotropin-releasing hormone receptor 2) (CRH-R-2) (CRH-R2) CRF2 receptor, beta isoform (Corticotropin releasing hormone receptor 2, isoform CRA_a) Corticotropin releasing hormone receptor 2 CRF2 receptor isoform G (CRH receptor 2 variant B)
Synonyms	CRH2R hCG_1811942 CRF2R tcag7.680
Description	FUNCTION: G-protein coupled receptor for CRH (corticotropin-releasing factor), UCN (urocortin), UCN2 and UCN3. Has high affinity for UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels.
Accessions	ENST00000348438.8 [Q13324-2] ENST00000471646.6 [Q13324-1] ENST00000506074.6 [Q13324-4] B3SXS9 C9JZM9 ENST00000445981.5 Q99432 A0A090N7T4 ENST00000452278.5 Q13324 ENST00000341843.8 [Q13324-3] F2Z2M6 ENST00000423776.1

CRHR2 report