CHRM4 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of CHRM4 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CHRM4 at tissue level.

III. Associated gene sets

GO_0007165Biological processsignal transduction
GO_0007197Biological processadenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway
GO_0007268Biological processchemical synaptic transmission
GO_0007213Biological processG protein-coupled acetylcholine receptor signaling pathway
GO_0098664Biological processG protein-coupled serotonin receptor signaling pathway
GO_0040012Biological processregulation of locomotion
GO_0007166Biological processcell surface receptor signaling pathway
GO_0007187Biological processG protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO_0045211Cellular componentpostsynaptic membrane
GO_0030425Cellular componentdendrite
GO_0005886Cellular componentplasma membrane
GO_0045202Cellular componentsynapse
GO_0004993Molecular functionG protein-coupled serotonin receptor activity
GO_0016907Molecular functionG protein-coupled acetylcholine receptor activity

IV. Literature review

[source]
Gene nameCHRM4
Protein nameMuscarinic acetylcholine receptor M4
Muscarinic acetylcholine receptor
Synonyms
DescriptionFUNCTION: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is inhibition of adenylate cyclase.

FUNCTION: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. .

AccessionsQ96RG8
P08173
ENST00000433765.3
ENST00000682254.1