I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| macrophage | 6 studies | 19% ± 3% | |
| classical monocyte | 5 studies | 21% ± 5% | |
| myeloid cell | 3 studies | 17% ± 0% | |
| non-classical monocyte | 3 studies | 17% ± 1% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| macrophage | 6 studies | 19% ± 3% | |
| classical monocyte | 5 studies | 21% ± 5% | |
| myeloid cell | 3 studies | 17% ± 0% | |
| non-classical monocyte | 3 studies | 17% ± 1% |
Insufficient scRNA-seq data for expression of SIGLEC9 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 100% | 690.88 | 578 / 578 | 93% | 5.54 | 1074 / 1155 |
| breast | 81% | 164.93 | 372 / 459 | 96% | 4.47 | 1078 / 1118 |
| ovary | 88% | 167.14 | 159 / 180 | 85% | 3.95 | 366 / 430 |
| bladder | 90% | 172.10 | 19 / 21 | 67% | 2.91 | 338 / 504 |
| adrenal gland | 99% | 376.60 | 256 / 258 | 58% | 1.99 | 134 / 230 |
| intestine | 83% | 145.51 | 801 / 966 | 69% | 2.56 | 366 / 527 |
| kidney | 58% | 98.85 | 52 / 89 | 91% | 5.83 | 818 / 901 |
| liver | 81% | 155.24 | 182 / 226 | 61% | 1.86 | 249 / 406 |
| stomach | 58% | 89.98 | 209 / 359 | 80% | 3.12 | 228 / 286 |
| thymus | 59% | 72.91 | 383 / 653 | 79% | 2.36 | 476 / 605 |
| uterus | 56% | 66.52 | 96 / 170 | 78% | 2.56 | 360 / 459 |
| brain | 38% | 72.74 | 1005 / 2642 | 94% | 8.53 | 665 / 705 |
| pancreas | 39% | 50.01 | 128 / 328 | 92% | 4.81 | 163 / 178 |
| esophagus | 51% | 76.00 | 744 / 1445 | 69% | 1.84 | 126 / 183 |
| prostate | 66% | 97.85 | 162 / 245 | 52% | 0.97 | 260 / 502 |
| skin | 15% | 14.76 | 273 / 1809 | 89% | 4.96 | 420 / 472 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 13.88 | 29 / 29 |
| spleen | 100% | 1711.29 | 241 / 241 | 0% | 0 | 0 / 0 |
| adipose | 95% | 346.40 | 1141 / 1204 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 93% | 3.38 | 42 / 45 |
| peripheral blood | 82% | 3315.60 | 761 / 929 | 0% | 0 | 0 / 0 |
| blood vessel | 69% | 168.08 | 919 / 1335 | 0% | 0 | 0 / 0 |
| heart | 58% | 94.13 | 501 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 35% | 0.84 | 28 / 80 |
| muscle | 7% | 6.00 | 57 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0007155 | Biological process | cell adhesion |
| GO_0007166 | Biological process | cell surface receptor signaling pathway |
| GO_0030667 | Cellular component | secretory granule membrane |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0030246 | Molecular function | carbohydrate binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0033691 | Molecular function | sialic acid binding |
| Gene name | SIGLEC9 |
| Protein name | Sialic acid-binding Ig-like lectin 9 (Siglec-9) (CDw329) (Protein FOAP-9) (CD antigen CD329) Sialic acid binding Ig like lectin 9 |
| Synonyms | UNQ668/PRO1302 |
| Description | FUNCTION: Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- or alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. |
| Accessions | Q9Y336 ENST00000250360.8 [Q9Y336-1] ENST00000599948.1 ENST00000440804.7 [Q9Y336-2] M0R2D4 |
