I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| B cell | 21 studies | 26% ± 6% | |
| memory B cell | 12 studies | 22% ± 5% | |
| naive B cell | 3 studies | 23% ± 4% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| B cell | 21 studies | 26% ± 6% | |
| memory B cell | 12 studies | 22% ± 5% | |
| naive B cell | 3 studies | 23% ± 4% |
Insufficient scRNA-seq data for expression of FCRL2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 94% | 129.15 | 543 / 578 | 51% | 2.08 | 590 / 1155 |
| spleen | 100% | 5747.69 | 241 / 241 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 90% | 57.25 | 26 / 29 |
| peripheral blood | 87% | 257.20 | 812 / 929 | 0% | 0 | 0 / 0 |
| intestine | 56% | 966.02 | 539 / 966 | 16% | 0.80 | 84 / 527 |
| stomach | 47% | 60.57 | 167 / 359 | 22% | 0.73 | 62 / 286 |
| kidney | 44% | 71.46 | 39 / 89 | 4% | 0.20 | 37 / 901 |
| liver | 39% | 20.86 | 88 / 226 | 4% | 0.28 | 17 / 406 |
| tonsil | 0% | 0 | 0 / 0 | 40% | 1.24 | 18 / 45 |
| breast | 23% | 18.11 | 107 / 459 | 15% | 0.59 | 165 / 1118 |
| prostate | 32% | 40.99 | 78 / 245 | 6% | 0.14 | 29 / 502 |
| thymus | 22% | 111.92 | 146 / 653 | 14% | 0.68 | 83 / 605 |
| esophagus | 20% | 24.58 | 287 / 1445 | 14% | 0.44 | 26 / 183 |
| bladder | 19% | 46.81 | 4 / 21 | 13% | 0.82 | 68 / 504 |
| pancreas | 1% | 0.43 | 4 / 328 | 24% | 1.25 | 43 / 178 |
| skin | 0% | 0.27 | 6 / 1809 | 21% | 1.08 | 101 / 472 |
| adipose | 16% | 22.89 | 196 / 1204 | 0% | 0 | 0 / 0 |
| uterus | 6% | 2.24 | 10 / 170 | 10% | 0.25 | 46 / 459 |
| ovary | 7% | 3.26 | 13 / 180 | 2% | 0.03 | 9 / 430 |
| blood vessel | 6% | 23.22 | 85 / 1335 | 0% | 0 | 0 / 0 |
| heart | 5% | 4.92 | 42 / 861 | 0% | 0 | 0 / 0 |
| adrenal gland | 4% | 1.37 | 10 / 258 | 1% | 0.01 | 2 / 230 |
| eye | 0% | 0 | 0 / 0 | 3% | 0.04 | 2 / 80 |
| brain | 0% | 0.17 | 9 / 2642 | 0% | 0.10 | 3 / 705 |
| muscle | 0% | 0.12 | 1 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006955 | Biological process | immune response |
| GO_0007267 | Biological process | cell-cell signaling |
| GO_0007166 | Biological process | cell surface receptor signaling pathway |
| GO_0009986 | Cellular component | cell surface |
| GO_0009897 | Cellular component | external side of plasma membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0004888 | Molecular function | transmembrane signaling receptor activity |
| GO_0035591 | Molecular function | signaling adaptor activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0019903 | Molecular function | protein phosphatase binding |
| Gene name | FCRL2 |
| Protein name | Fc receptor-like protein 2 (FcR-like protein 2) (FcRL2) (Fc receptor homolog 2) (FcRH2) (IFGP family protein 4) (Immunoglobulin receptor translocation-associated protein 4) (SH2 domain-containing phosphatase anchor protein 1) (CD antigen CD307b) |
| Synonyms | FCRH2 IRTA4 UNQ9236/PRO31998 IFGP4 SPAP1 |
| Description | FUNCTION: May have an regulatory role in normal and neoplastic B cell development. . |
| Accessions | ENST00000361516.8 [Q96LA5-1] ENST00000469986.1 [Q96LA5-3] Q96LA5 ENST00000368181.4 [Q96LA5-5] |
