CABIN1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006334Biological processnucleosome assembly
GO_0007166Biological processcell surface receptor signaling pathway
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0016235Cellular componentaggresome
GO_0005634Cellular componentnucleus
GO_0004864Molecular functionprotein phosphatase inhibitor activity
GO_0031491Molecular functionnucleosome binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCABIN1
Protein nameCalcineurin binding protein 1
CABIN1 protein
Calcineurin-binding protein cabin-1 (Calcineurin inhibitor) (CAIN)
SynonymshCG_41092
KIAA0330
DescriptionFUNCTION: May be required for replication-independent chromatin assembly. May serve as a negative regulator of T-cell receptor (TCR) signaling via inhibition of calcineurin. Inhibition of activated calcineurin is dependent on both PKC and calcium signals. Acts as a negative regulator of p53/TP53 by keeping p53 in an inactive state on chromatin at promoters of a subset of it's target genes. .

AccessionsENST00000405822.6 [Q9Y6J0-2]
B5MEB3
Q9Y6J0
ENST00000337989.11
C9J068
ENST00000445422.5
ENST00000454754.5
ENST00000263119.10 [Q9Y6J0-1]
A0A087WWW8
C9JT60
ENST00000398319.6 [Q9Y6J0-1]
ENST00000617531.4
Q05C66