C3AR1 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of C3AR1 at tissue level.

III. Associated gene sets

GO_0006954Biological processinflammatory response
GO_0007200Biological processphospholipase C-activating G protein-coupled receptor signaling pathway
GO_0019722Biological processcalcium-mediated signaling
GO_0045766Biological processpositive regulation of angiogenesis
GO_0006935Biological processchemotaxis
GO_0010759Biological processpositive regulation of macrophage chemotaxis
GO_0038178Biological processcomplement component C5a signaling pathway
GO_0007186Biological processG protein-coupled receptor signaling pathway
GO_0007204Biological processpositive regulation of cytosolic calcium ion concentration
GO_0008015Biological processblood circulation
GO_0010575Biological processpositive regulation of vascular endothelial growth factor production
GO_0090023Biological processpositive regulation of neutrophil chemotaxis
GO_0002430Biological processcomplement receptor mediated signaling pathway
GO_0035579Cellular componentspecific granule membrane
GO_0005886Cellular componentplasma membrane
GO_0035577Cellular componentazurophil granule membrane
GO_0004930Molecular functionG protein-coupled receptor activity
GO_0004878Molecular functioncomplement component C5a receptor activity
GO_0004876Molecular functioncomplement component C3a receptor activity

IV. Literature review

[source]
Gene nameC3AR1
Protein nameC3a anaphylatoxin chemotactic receptor (C3AR) (C3a-R)
C3a anaphylatoxin chemotactic receptor
SynonymsAZ3B
HNFAG09
C3R1
hCG_22220
DescriptionFUNCTION: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.

FUNCTION: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production. .

FUNCTION: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production. .

AccessionsF5GZE6
Q16581
A8K2H7
ENST00000307637.5
ENST00000546241.1