Name | Number of supported studies | Average coverage | |
---|---|---|---|
macrophage | 31 studies | 34% ± 12% | |
non-classical monocyte | 20 studies | 27% ± 6% | |
classical monocyte | 13 studies | 24% ± 6% | |
myeloid cell | 10 studies | 28% ± 8% | |
monocyte | 9 studies | 28% ± 11% | |
microglial cell | 7 studies | 34% ± 21% | |
mononuclear phagocyte | 6 studies | 31% ± 11% | |
conventional dendritic cell | 6 studies | 21% ± 4% | |
alveolar macrophage | 5 studies | 23% ± 13% | |
dendritic cell | 4 studies | 27% ± 14% | |
tissue-resident macrophage | 3 studies | 32% ± 8% | |
neutrophil | 3 studies | 21% ± 4% |
Insufficient scRNA-seq data for expression of C3AR1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
lung | 98% | 1914.48 | 569 / 578 | 89% | 19.29 | 1025 / 1155 |
breast | 85% | 580.55 | 388 / 459 | 95% | 19.61 | 1063 / 1118 |
intestine | 95% | 580.82 | 915 / 966 | 68% | 9.29 | 360 / 527 |
bladder | 95% | 494.90 | 20 / 21 | 63% | 9.63 | 316 / 504 |
adrenal gland | 92% | 781.98 | 237 / 258 | 51% | 5.59 | 118 / 230 |
brain | 46% | 270.18 | 1210 / 2642 | 96% | 35.05 | 680 / 705 |
prostate | 73% | 313.28 | 178 / 245 | 66% | 5.56 | 331 / 502 |
stomach | 64% | 281.62 | 230 / 359 | 74% | 12.72 | 212 / 286 |
uterus | 66% | 263.64 | 113 / 170 | 70% | 8.58 | 321 / 459 |
kidney | 46% | 252.73 | 41 / 89 | 86% | 21.19 | 778 / 901 |
esophagus | 67% | 355.12 | 965 / 1445 | 65% | 7.17 | 119 / 183 |
ovary | 51% | 209.01 | 91 / 180 | 81% | 13.16 | 347 / 430 |
pancreas | 39% | 150.94 | 129 / 328 | 85% | 16.78 | 151 / 178 |
thymus | 48% | 199.92 | 313 / 653 | 73% | 8.47 | 442 / 605 |
skin | 25% | 84.17 | 445 / 1809 | 83% | 15.76 | 393 / 472 |
lymph node | 0% | 0 | 0 / 0 | 100% | 29.40 | 29 / 29 |
spleen | 98% | 2046.11 | 236 / 241 | 0% | 0 | 0 / 0 |
adipose | 98% | 1367.38 | 1176 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 87% | 931.07 | 1159 / 1335 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 84% | 12.62 | 38 / 45 |
peripheral blood | 81% | 5888.03 | 756 / 929 | 0% | 0 | 0 / 0 |
liver | 25% | 105.21 | 57 / 226 | 48% | 4.60 | 194 / 406 |
heart | 45% | 212.28 | 388 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 29% | 2.41 | 23 / 80 |
muscle | 8% | 22.76 | 67 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0006954 | Biological process | inflammatory response |
GO_0007200 | Biological process | phospholipase C-activating G protein-coupled receptor signaling pathway |
GO_0019722 | Biological process | calcium-mediated signaling |
GO_0045766 | Biological process | positive regulation of angiogenesis |
GO_0006935 | Biological process | chemotaxis |
GO_0010759 | Biological process | positive regulation of macrophage chemotaxis |
GO_0038178 | Biological process | complement component C5a signaling pathway |
GO_0007186 | Biological process | G protein-coupled receptor signaling pathway |
GO_0007204 | Biological process | positive regulation of cytosolic calcium ion concentration |
GO_0008015 | Biological process | blood circulation |
GO_0010575 | Biological process | positive regulation of vascular endothelial growth factor production |
GO_0090023 | Biological process | positive regulation of neutrophil chemotaxis |
GO_0002430 | Biological process | complement receptor mediated signaling pathway |
GO_0035579 | Cellular component | specific granule membrane |
GO_0005886 | Cellular component | plasma membrane |
GO_0035577 | Cellular component | azurophil granule membrane |
GO_0004930 | Molecular function | G protein-coupled receptor activity |
GO_0004878 | Molecular function | complement component C5a receptor activity |
GO_0004876 | Molecular function | complement component C3a receptor activity |
Gene name | C3AR1 |
Protein name | C3a anaphylatoxin chemotactic receptor (C3AR) (C3a-R) C3a anaphylatoxin chemotactic receptor |
Synonyms | AZ3B HNFAG09 C3R1 hCG_22220 |
Description | FUNCTION: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production. FUNCTION: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production. . FUNCTION: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production. . |
Accessions | F5GZE6 Q16581 A8K2H7 ENST00000307637.5 ENST00000546241.1 |