TAAR1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of TAAR1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of TAAR1 at tissue level.

III. Associated gene sets

GO_0007186Biological processG protein-coupled receptor signaling pathway
GO_0005886Cellular componentplasma membrane
GO_0001594Molecular functiontrace-amine receptor activity
GO_0004930Molecular functionG protein-coupled receptor activity

IV. Literature review

[source]
Gene nameTAAR1
Protein nameTrace amine-associated receptor 1 (TaR-1) (Trace amine receptor 1)
SynonymsTA1
TAR1
TRAR1
DescriptionFUNCTION: Receptor for trace amines, including beta-phenylethylamine (b-PEA), p-tyramine (p-TYR), octopamine and tryptamine, with highest affinity for b-PEA and p-TYR. Unresponsive to classical biogenic amines, such as epinephrine and histamine and only partially activated by dopamine and serotonin. Trace amines are biogenic amines present in very low levels in mammalian tissues. Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative. Trace amines are likely to be involved in a variety of physiological functions that have yet to be fully understood. The signal transduced by this receptor is mediated by the G(s)-class of G-proteins which activate adenylate cyclase. .

AccessionsENST00000275216.3
Q96RJ0