CXCR6 | OmnibusX

Name	Number of supported studies	Average coverage
regulatory T cell	9 studies	28% ± 7%	Explore
CD8-positive, alpha-beta T cell	8 studies	25% ± 5%	Explore
mucosal invariant T cell	7 studies	22% ± 4%	Explore
T cell	7 studies	22% ± 7%	Explore
CD4-positive, alpha-beta T cell	5 studies	21% ± 6%	Explore
exhausted T cell	4 studies	23% ± 6%	Explore
CD16-negative, CD56-bright natural killer cell, human	4 studies	25% ± 8%	Explore
CD4-positive helper T cell	3 studies	24% ± 4%	Explore
gamma-delta T cell	3 studies	19% ± 3%	Explore
CD4-positive, alpha-beta cytotoxic T cell	3 studies	25% ± 4%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of CXCR6 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
lung	100%	323.60	576 / 578	84%	6.76	971 / 1155
stomach	98%	227.77	352 / 359	72%	5.42	207 / 286
intestine	93%	217.63	898 / 966	70%	4.23	369 / 527
uterus	96%	90.39	164 / 170	66%	5.57	301 / 459
bladder	90%	143.05	19 / 21	57%	3.88	289 / 504
thymus	98%	157.05	642 / 653	49%	3.15	295 / 605
esophagus	82%	85.86	1192 / 1445	59%	3.37	108 / 183
prostate	96%	113.91	236 / 245	43%	1.80	214 / 502
breast	77%	68.92	352 / 459	60%	3.91	667 / 1118
skin	70%	50.04	1271 / 1809	57%	6.01	267 / 472
pancreas	66%	38.55	216 / 328	60%	4.20	106 / 178
ovary	89%	71.07	161 / 180	34%	1.54	145 / 430
kidney	60%	61.22	53 / 89	62%	4.45	562 / 901
liver	81%	54.97	184 / 226	32%	1.80	128 / 406
spleen	100%	1160.39	241 / 241	0%	0	0 / 0
lymph node	0%	0	0 / 0	97%	33.47	28 / 29
peripheral blood	92%	229.66	851 / 929	0%	0	0 / 0
tonsil	0%	0	0 / 0	91%	12.69	41 / 45
blood vessel	89%	92.39	1188 / 1335	0%	0	0 / 0
muscle	88%	369.68	709 / 803	0%	0	0 / 0
adipose	85%	100.47	1022 / 1204	0%	0	0 / 0
heart	76%	65.15	655 / 861	0%	0	0 / 0
adrenal gland	68%	41.85	176 / 258	7%	0.28	17 / 230
brain	6%	3.52	169 / 2642	7%	0.29	48 / 705
eye	0%	0	0 / 0	13%	0.84	10 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0006955	Biological process	immune response
GO_0007186	Biological process	G protein-coupled receptor signaling pathway
GO_0070098	Biological process	chemokine-mediated signaling pathway
GO_0007204	Biological process	positive regulation of cytosolic calcium ion concentration
GO_0006954	Biological process	inflammatory response
GO_0019722	Biological process	calcium-mediated signaling
GO_0019079	Biological process	viral genome replication
GO_0060326	Biological process	cell chemotaxis
GO_0009897	Cellular component	external side of plasma membrane
GO_0005886	Cellular component	plasma membrane
GO_0016493	Molecular function	C-C chemokine receptor activity
GO_0019957	Molecular function	C-C chemokine binding
GO_0015026	Molecular function	coreceptor activity
GO_0016494	Molecular function	C-X-C chemokine receptor activity
GO_0004930	Molecular function	G protein-coupled receptor activity

Gene name	CXCR6
Protein name	C-X-C chemokine receptor type 6 (CXC-R6) (CXCR-6) (CDw186) (G-protein coupled receptor STRL33) (G-protein coupled receptor bonzo) (CD antigen CD186) C-X-C chemokine receptor type 6 (G-protein coupled receptor bonzo)
Synonyms	STRL33 BONZO hCG_15326 TYMSTR
Description	FUNCTION: Receptor for the C-X-C chemokine CXCL16. Used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1. FUNCTION: Receptor for the C-X-C chemokine CXCL16. Used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1. .
Accessions	ENST00000438735.1 ENST00000458629.1 ENST00000457814.1 ENST00000304552.5 A0N0N3 O00574

CXCR6 report