GPR6 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of GPR6 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of GPR6 at tissue level.

III. Associated gene sets

GO_0003376Biological processsphingosine-1-phosphate receptor signaling pathway
GO_0007186Biological processG protein-coupled receptor signaling pathway
GO_0007204Biological processpositive regulation of cytosolic calcium ion concentration
GO_0019222Biological processregulation of metabolic process
GO_0007189Biological processadenylate cyclase-activating G protein-coupled receptor signaling pathway
GO_0005886Cellular componentplasma membrane
GO_0005737Cellular componentcytoplasm
GO_0004930Molecular functionG protein-coupled receptor activity
GO_0038036Molecular functionsphingosine-1-phosphate receptor activity

IV. Literature review

[source]
Gene nameGPR6
Protein nameG protein-coupled receptor 6
G-protein coupled receptor 6 (Sphingosine 1-phosphate receptor GPR6)
G protein-coupled receptor 6 (HCG1783112)
SynonymshCG_1783112
DescriptionFUNCTION: Orphan receptor with constitutive G(s) signaling activity that activate cyclic AMP. Promotes neurite outgrowth and blocks myelin inhibition in neurons (By similarity). .

AccessionsF1DAM6
E7EP76
P46095
ENST00000275169.5 [P46095-1]
ENST00000414000.3 [P46095-2]