MTNR1A report

I. Expression across cell types

Insufficient scRNA-seq data for expression of MTNR1A at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of MTNR1A at tissue level.

III. Associated gene sets

GO_0007617Biological processmating behavior
GO_0007186Biological processG protein-coupled receptor signaling pathway
GO_0007193Biological processadenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
GO_0007623Biological processcircadian rhythm
GO_0007187Biological processG protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO_0043235Cellular componentreceptor complex
GO_0005886Cellular componentplasma membrane
GO_0042562Molecular functionhormone binding
GO_0097159Molecular functionorganic cyclic compound binding
GO_0008502Molecular functionmelatonin receptor activity
GO_0004930Molecular functionG protein-coupled receptor activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameMTNR1A
Protein nameMelatonin receptor type 1A
Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor)
Synonyms
DescriptionFUNCTION: High affinity receptor for melatonin. Likely to mediate the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.

FUNCTION: High affinity receptor for melatonin. Likely to mediate the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity. .

FUNCTION: High affinity receptor for melatonin. Likely to mediate the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity. .

AccessionsENST00000307161.5
ENST00000703170.1
Q8WZ72
Q29RX9
P48039