TAS2R46 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of TAS2R46 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of TAS2R46 at tissue level.

III. Associated gene sets

GO_0007186Biological processG protein-coupled receptor signaling pathway
GO_0001580Biological processdetection of chemical stimulus involved in sensory perception of bitter taste
GO_0060170Cellular componentciliary membrane
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0004930Molecular functionG protein-coupled receptor activity
GO_0033038Molecular functionbitter taste receptor activity

IV. Literature review

[source]
Gene nameTAS2R46
Protein nameTaste receptor type 2 member 46
Taste receptor type 2 member 46 (T2R46) (Taste receptor type 2 member 54) (T2R54)
Synonyms
DescriptionFUNCTION: Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity). In airway epithelial cells, binding of bitter compounds increases the intracellular calcium ion concentration and stimulates ciliary beat frequency (By similarity). .

AccessionsP59540
ENST00000574263.1
ENST00000533467.1
A0A0J9YY42
ENST00000633803.1