Insufficient scRNA-seq data for expression of CMKLR2 at single-cell level.
Insufficient scRNA-seq data for expression of CMKLR2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
adrenal gland | 89% | 250.16 | 229 / 258 | 70% | 6.94 | 162 / 230 |
esophagus | 85% | 195.38 | 1234 / 1445 | 50% | 2.23 | 92 / 183 |
skin | 100% | 602.46 | 1805 / 1809 | 31% | 1.01 | 146 / 472 |
ovary | 67% | 113.16 | 120 / 180 | 48% | 1.64 | 206 / 430 |
breast | 33% | 25.53 | 150 / 459 | 61% | 2.49 | 684 / 1118 |
heart | 74% | 76.20 | 634 / 861 | 0% | 0 | 0 / 0 |
bladder | 38% | 34.24 | 8 / 21 | 32% | 1.60 | 160 / 504 |
adipose | 69% | 105.15 | 833 / 1204 | 0% | 0 | 0 / 0 |
kidney | 28% | 17.27 | 25 / 89 | 41% | 1.01 | 369 / 901 |
uterus | 28% | 23.14 | 48 / 170 | 41% | 2.01 | 186 / 459 |
pancreas | 0% | 0 | 0 / 328 | 53% | 1.81 | 95 / 178 |
lung | 15% | 10.61 | 84 / 578 | 37% | 1.24 | 424 / 1155 |
tonsil | 0% | 0 | 0 / 0 | 51% | 3.15 | 23 / 45 |
intestine | 26% | 18.62 | 255 / 966 | 19% | 0.64 | 101 / 527 |
thymus | 33% | 21.87 | 216 / 653 | 12% | 0.33 | 71 / 605 |
brain | 22% | 27.20 | 577 / 2642 | 20% | 1.05 | 138 / 705 |
stomach | 8% | 4.85 | 30 / 359 | 26% | 0.63 | 75 / 286 |
blood vessel | 35% | 35.02 | 461 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 21% | 0.35 | 6 / 29 |
muscle | 20% | 12.39 | 158 / 803 | 0% | 0 | 0 / 0 |
prostate | 9% | 6.42 | 21 / 245 | 2% | 0.03 | 12 / 502 |
liver | 0% | 0 | 0 / 226 | 5% | 0.31 | 20 / 406 |
eye | 0% | 0 | 0 / 0 | 4% | 0.07 | 3 / 80 |
peripheral blood | 0% | 0.23 | 4 / 929 | 0% | 0 | 0 / 0 |
spleen | 0% | 0.29 | 1 / 241 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0007186 | Biological process | G protein-coupled receptor signaling pathway |
GO_0007218 | Biological process | neuropeptide signaling pathway |
GO_0042593 | Biological process | glucose homeostasis |
GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005886 | Cellular component | plasma membrane |
GO_0043005 | Cellular component | neuron projection |
GO_0042923 | Molecular function | neuropeptide binding |
GO_0004930 | Molecular function | G protein-coupled receptor activity |
GO_0097003 | Molecular function | adipokinetic hormone receptor activity |
GO_0097004 | Molecular function | adipokinetic hormone binding |
GO_0005515 | Molecular function | protein binding |
Gene name | CMKLR2 |
Protein name | Chemerin chemokine-like receptor 2 (Chemerin-like receptor 2) Chemerin-like receptor 2 (Chemerin chemokine-like receptor 2) (Chemokine-like receptor 2) (G-protein coupled receptor 1) |
Synonyms | GPR1 |
Description | FUNCTION: Receptor for chemoattractant adipokine chemerin/RARRES2 suggesting a role for this receptor in the regulation of inflammation and energy homesotasis . Signals mainly via beta-arrestin pathway. Binding of RARRES2 activates weakly G proteins, calcium mobilization and MAPK1/MAPK3 (ERK1/2) phosphorylation too . Acts also as a receptor for TAFA1, mediates its effects on neuronal stem-cell proliferation and differentiation via the activation of ROCK/ERK and ROCK/STAT3 signaling pathway (By similarity). .; FUNCTION: (Microbial infection) Coreceptor for HIV-1. . |
Accessions | ENST00000637600.1 ENST00000451790.5 C9JQB7 C9JCK1 ENST00000437420.5 C9JKF3 ENST00000439932.5 ENST00000621141.5 ENST00000638116.1 ENST00000637075.1 ENST00000636848.1 ENST00000638027.1 ENST00000636284.1 ENST00000636896.1 ENST00000635908.1 ENST00000411719.1 C9JSU0 ENST00000636918.1 ENST00000638097.1 C9J456 ENST00000458440.1 ENST00000407325.6 ENST00000442134.1 C9JFR8 P46091 |