Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| peripheral blood | 9 studies | 27% ± 10% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 100% | 897.72 | 578 / 578 | 89% | 9.06 | 1029 / 1155 |
| thymus | 99% | 221.64 | 645 / 653 | 88% | 11.48 | 534 / 605 |
| breast | 92% | 193.39 | 420 / 459 | 61% | 4.54 | 678 / 1118 |
| stomach | 72% | 121.26 | 259 / 359 | 77% | 5.57 | 220 / 286 |
| bladder | 76% | 185.95 | 16 / 21 | 72% | 5.56 | 365 / 504 |
| intestine | 61% | 271.51 | 586 / 966 | 76% | 5.49 | 399 / 527 |
| kidney | 55% | 95.94 | 49 / 89 | 79% | 6.07 | 712 / 901 |
| esophagus | 63% | 84.72 | 908 / 1445 | 70% | 4.87 | 128 / 183 |
| uterus | 51% | 52.91 | 87 / 170 | 75% | 5.90 | 343 / 459 |
| prostate | 68% | 90.32 | 167 / 245 | 45% | 2.14 | 226 / 502 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 74.78 | 29 / 29 |
| peripheral blood | 100% | 17079.84 | 929 / 929 | 0% | 0 | 0 / 0 |
| spleen | 100% | 4164.03 | 241 / 241 | 0% | 0 | 0 / 0 |
| pancreas | 9% | 10.27 | 31 / 328 | 89% | 10.73 | 159 / 178 |
| adipose | 97% | 266.77 | 1173 / 1204 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 93% | 13.18 | 42 / 45 |
| skin | 23% | 21.86 | 422 / 1809 | 68% | 8.22 | 323 / 472 |
| liver | 38% | 42.81 | 85 / 226 | 41% | 2.57 | 168 / 406 |
| adrenal gland | 47% | 44.49 | 121 / 258 | 31% | 1.33 | 71 / 230 |
| ovary | 7% | 6.41 | 12 / 180 | 53% | 2.28 | 226 / 430 |
| brain | 8% | 6.86 | 208 / 2642 | 26% | 1.00 | 184 / 705 |
| blood vessel | 34% | 50.01 | 451 / 1335 | 0% | 0 | 0 / 0 |
| heart | 29% | 28.69 | 249 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 15% | 0.74 | 12 / 80 |
| muscle | 7% | 5.12 | 53 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006955 | Biological process | immune response |
| GO_0003376 | Biological process | sphingosine-1-phosphate receptor signaling pathway |
| GO_0007186 | Biological process | G protein-coupled receptor signaling pathway |
| GO_0007189 | Biological process | adenylate cyclase-activating G protein-coupled receptor signaling pathway |
| GO_0007204 | Biological process | positive regulation of cytosolic calcium ion concentration |
| GO_0019222 | Biological process | regulation of metabolic process |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005739 | Cellular component | mitochondrion |
| GO_0004930 | Molecular function | G protein-coupled receptor activity |
| GO_0038036 | Molecular function | sphingosine-1-phosphate receptor activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0008289 | Molecular function | lipid binding |
| Gene name | S1PR4 |
| Protein name | Sphingosine 1-phosphate receptor 4 (S1P receptor 4) (S1P4) (Endothelial differentiation G-protein coupled receptor 6) (Sphingosine 1-phosphate receptor Edg-6) (S1P receptor Edg-6) |
| Synonyms | EDG6 |
| Description | FUNCTION: Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. May be involved in cell migration processes that are specific for lymphocytes. . |
| Accessions | ENST00000246115.5 O95977 |