NTSR1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of NTSR1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of NTSR1 at tissue level.

III. Associated gene sets

GO_0070779Biological processD-aspartate import across plasma membrane
GO_0007218Biological processneuropeptide signaling pathway
GO_0014049Biological processpositive regulation of glutamate secretion
GO_0007612Biological processlearning
GO_0008344Biological processadult locomotory behavior
GO_0010628Biological processpositive regulation of gene expression
GO_0098712Biological processL-glutamate import across plasma membrane
GO_0090238Biological processpositive regulation of arachidonic acid secretion
GO_0060732Biological processpositive regulation of inositol phosphate biosynthetic process
GO_0043576Biological processregulation of respiratory gaseous exchange
GO_0003254Biological processregulation of membrane depolarization
GO_0003085Biological processnegative regulation of systemic arterial blood pressure
GO_0007186Biological processG protein-coupled receptor signaling pathway
GO_0033993Biological processresponse to lipid
GO_0043066Biological processnegative regulation of apoptotic process
GO_0007268Biological processchemical synaptic transmission
GO_0050965Biological processdetection of temperature stimulus involved in sensory perception of pain
GO_0097151Biological processpositive regulation of inhibitory postsynaptic potential
GO_0071545Biological processinositol phosphate catabolic process
GO_0051281Biological processpositive regulation of release of sequestered calcium ion into cytosol
GO_0001659Biological processtemperature homeostasis
GO_0014054Biological processpositive regulation of gamma-aminobutyric acid secretion
GO_0051280Biological processnegative regulation of release of sequestered calcium ion into cytosol
GO_0043065Biological processpositive regulation of apoptotic process
GO_0005886Cellular componentplasma membrane
GO_0045121Cellular componentmembrane raft
GO_0043197Cellular componentdendritic spine
GO_0043198Cellular componentdendritic shaft
GO_0009898Cellular componentcytoplasmic side of plasma membrane
GO_0043204Cellular componentperikaryon
GO_0043195Cellular componentterminal bouton
GO_0005794Cellular componentGolgi apparatus
GO_0009986Cellular componentcell surface
GO_0005783Cellular componentendoplasmic reticulum
GO_0032280Cellular componentsymmetric synapse
GO_0004930Molecular functionG protein-coupled receptor activity
GO_0044877Molecular functionprotein-containing complex binding
GO_0042802Molecular functionidentical protein binding
GO_0016492Molecular functionG protein-coupled neurotensin receptor activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameNTSR1
Protein nameNeurotensin receptor type 1 (NT-R-1) (NTR1) (High-affinity levocabastine-insensitive neurotensin receptor) (NTRH)
SynonymsNTRR
DescriptionFUNCTION: G-protein coupled receptor for the tridecapeptide neurotensin (NTS) . Signaling is effected via G proteins that activate a phosphatidylinositol-calcium second messenger system. Signaling leads to the activation of downstream MAP kinases and protects cells against apoptosis . .

AccessionsP30989
ENST00000370501.4