NPY4R report

I. Expression across cell types

Insufficient scRNA-seq data for expression of NPY4R at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of NPY4R at tissue level.

III. Associated gene sets

GO_0007186Biological processG protein-coupled receptor signaling pathway
GO_0007218Biological processneuropeptide signaling pathway
GO_0005886Cellular componentplasma membrane
GO_0043005Cellular componentneuron projection
GO_0016020Cellular componentmembrane
GO_0042923Molecular functionneuropeptide binding
GO_0017046Molecular functionpeptide hormone binding
GO_0004930Molecular functionG protein-coupled receptor activity
GO_0001602Molecular functionpancreatic polypeptide receptor activity

IV. Literature review

[source]
Gene nameNPY4R
Protein nameNeuropeptide Y receptor type 4 (NPY4-R) (Pancreatic polypeptide receptor 1) (PP1)
SynonymsPPYR1
DescriptionFUNCTION: G protein-coupled receptor for PPY/pancreatic polypeptide/PP, NPY/neuropeptide Y and PYY/peptide YY that is negatively coupled to cAMP . The rank order of affinity for these polypeptides and their derivatives is PP, PP (2-36) and [Ile-31, Gln-34] PP > [Pro-34] PYY > PYY and [Leu-31, Pro-34] NPY > NPY > PYY (3-36) and NPY (2-36) > PP (13-36) > PP (31-36) > NPY free acid. .

AccessionsENST00000374312.5
ENST00000612632.3
P50391