GPR61 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of GPR61 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of GPR61 at tissue level.

III. Associated gene sets

GO_0007186Biological processG protein-coupled receptor signaling pathway
GO_0038035Biological processligand-independent adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO_0010008Cellular componentendosome membrane
GO_0005768Cellular componentendosome
GO_0043235Cellular componentreceptor complex
GO_0005886Cellular componentplasma membrane
GO_0004930Molecular functionG protein-coupled receptor activity
GO_1990763Molecular functionarrestin family protein binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameGPR61
Protein nameG-protein coupled receptor 61 (Biogenic amine receptor-like G-protein coupled receptor)
G protein-coupled receptor 61
SynonymsGPCR3
BALGR
DescriptionFUNCTION: Orphan G-protein coupled receptor. Constitutively activates the G(s)-alpha/cAMP signaling pathway . Shows a reciprocal regulatory interaction with the melatonin receptor MTNR1B most likely through receptor heteromerization . May be involved in the regulation of food intake and body weight (By similarity). .

AccessionsENST00000404129.6
ENST00000527748.5
G4XH66
ENST00000689084.1
ENST00000618721.5
A0A8I5KY74
ENST00000616874.2
Q9BZJ8
ENST00000469383.2